Circulating Immune Complexes After Splenectomy

Overview

Journal J Clin Pathol

Specialty Pathology

Date 1989 Jan 1

PMID 2784134

Authors

E A Donadi

I F Carvalho

R P Falcao

Affiliations

Soon will be listed here.

Abstract

Circulating immune complexes were evaluated in 25 patients (age range 10 to 46 years) who had undergone splenectomy for non-malignant conditions by studying a polyethylene glycol insoluble serum fraction. Although the extent of binding to Clq was within normal limits, these patients had increased concentrations of factor B in the immune complex serum fraction. These findings indicate that an unusual type of circulating immune complex may be detected after splenectomy, suggesting a possible role for the spleen in the removal of circulating immune complexes.

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