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Inhibitory Effect of and Isolated from the Faeces of Healthy Infants Against Nonfermentative Bacteria Causing Nosocomial Infections

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Publisher Elsevier
Date 2016 Nov 11
PMID 27830081
Citations 11
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Abstract

Nosocomial infection constitutes a major public health problem worldwide. Increasing antibiotic resistance of pathogens associated with nosocomial infections has also become a major therapeutic challenge for physicians. Thus, development of alternative treatment protocols, such as the use of probiotics, matters. The aim of this research was to determine the antagonistic properties of and isolated from the faeces of healthy infants against nonfermentative bacteria causing nosocomial infections. One hundred five samples of nosocomial infections were collected and processed for bacterial isolation and antimicrobial susceptibility testing following standard bacteriologic techniques. The antibiotic susceptibility test was performed by the disk diffusion method, and antagonistic effect of strains was investigated by well diffusion method. Of 105 samples, a total of 29 bacterial strains were identified as nonfermentative bacteria, including 17 and 12 . showed high resistance to tested antibiotics except ampicillin/sulbactam, and showed resistance to ampicillin/sulbactam and gentamicin and sensitive to amikacin and meropenem. had antagonistic properties against both and strains had considerable effects on preventing the growth of and strains However, further research is needed to better understanding of these effects on .

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References
1.
Coconnier M, Lievin V, Hemery E, Servin A . Antagonistic activity against Helicobacter infection in vitro and in vivo by the human Lactobacillus acidophilus strain LB. Appl Environ Microbiol. 1998; 64(11):4573-80. PMC: 106686. DOI: 10.1128/AEM.64.11.4573-4580.1998. View

2.
Ferrara A . Potentially multidrug-resistant non-fermentative Gram-negative pathogens causing nosocomial pneumonia. Int J Antimicrob Agents. 2006; 27(3):183-95. DOI: 10.1016/j.ijantimicag.2005.11.005. View

3.
Takahashi M, Taguchi H, Yamaguchi H, Osaki T, Komatsu A, Kamiya S . The effect of probiotic treatment with Clostridium butyricum on enterohemorrhagic Escherichia coli O157:H7 infection in mice. FEMS Immunol Med Microbiol. 2004; 41(3):219-26. DOI: 10.1016/j.femsim.2004.03.010. View

4.
Kotzampassi K, Giamarellos-Bourboulis E . Probiotics for infectious diseases: more drugs, less dietary supplementation. Int J Antimicrob Agents. 2012; 40(4):288-96. DOI: 10.1016/j.ijantimicag.2012.06.006. View

5.
Kamat U, Ferreira A, Savio R, Motghare D . Antimicrobial resistance among nosocomial isolates in a teaching hospital in goa. Indian J Community Med. 2009; 33(2):89-92. PMC: 2784633. DOI: 10.4103/0970-0218.40875. View