» Articles » PMID: 2779946

Neoplastic Characteristics of the DNA Found in the Plasma of Cancer Patients

Overview
Journal Oncology
Specialty Oncology
Date 1989 Jan 1
PMID 2779946
Citations 254
Authors
Affiliations
Soon will be listed here.
Abstract

About one third of patients with various malignant diseases were found to have extractable amounts of DNA in their plasma whereas no DNA could be detected in normal controls. Using the test established by one of us (M.B.), which is based on decreased strand stability of cancer cell DNA, we have found that several plasma DNA originate from cancer cells.

Citing Articles

Liquid Biopsy and Multidisciplinary Treatment for Esophageal Cancer.

Hoshi Y, Matsuda S, Takeuchi M, Kawakubo H, Kitagawa Y Cancers (Basel). 2025; 17(2).

PMID: 39857978 PMC: 11763614. DOI: 10.3390/cancers17020196.


Artificial intelligence and machine learning in cell-free-DNA-based diagnostics.

Tsui W, Ding S, Jiang P, Lo Y Genome Res. 2025; 35(1):1-19.

PMID: 39843210 PMC: 11789496. DOI: 10.1101/gr.278413.123.


Expanded knowledge of cell-free DNA biology: potential to broaden the clinical utility.

Che H, Stanley K, Jatsenko T, Thienpont B, Vermeesch J Extracell Vesicles Circ Nucl Acids. 2024; 3(3):216-234.

PMID: 39697489 PMC: 11648412. DOI: 10.20517/evcna.2022.21.


Perioperative Use of ctDNA to Guide Treatment for Urothelial Carcinoma: The Future is Now.

Stewart T, Chalfin H, Simon N, Tan A, Apolo A, McKay R Bladder Cancer. 2024; 10(3):183-198.

PMID: 39493820 PMC: 11530029. DOI: 10.3233/BLC-230105.


Liquid Biopsy in Neuropsychiatric Disorders: A Step Closer to Precision Medicine.

El-Ahmad P, Mendes-Silva A, Diniz B Mol Neurobiol. 2024; 62(3):3462-3479.

PMID: 39298102 DOI: 10.1007/s12035-024-04492-y.