Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets

Overview

Journal Int Sch Res Notices

Specialty Biology

Date 2016 Oct 25

PMID 27774509

Citations 7

Authors

I Diallo

C A Fall

B Ndiaye

M Mbaye

I Diedhiou

A R Ndiaye

P S Diawara

F Fall

P S Mbaye

S B Gning

Affiliations

Soon will be listed here.

Abstract

Primary hyperparathyroidism (PHPT) is rarely associated with the occurrence of acute or chronic pancreatitis. Hypercalcemia plays a major role in the pathogenesis. We report five cases of pancreatitis revealing PHPT. . This is a retrospective study of 4 years, including all patients admitted to intensive care unit or gastroenterology department, for an acute or chronic pancreatitis revealing primary hyperparathyroidism. . We included 5 patients, all female, with mean age 54 years [40-76 years]. The PHPT was in all cases revealed by acute pancreatitis (AP). This one was oedematous in four cases and severe in one case. It occurred twice in calcified chronic pancreatitis (CCP). There was hypercalcemia in all cases. The PHPT was associated with a high rate of parathyroid hormone in 4 cases. The secreting lesion was an adenoma in 5 cases. Two patients had in addition bilateral renal calcifications. The outcome was favorable in 4 patients among whom 3 have had parathyroid surgery. A death was noted by superinfection of necrosis in the case of severe AP. . The occurrence of pancreatitis during hyperparathyroidism is rare. Normal or elevated calcemia during acute or chronic pancreatitis should always get attention.

Citing Articles

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