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Release of Merozoite Dense Granules During Erythrocyte Invasion by Plasmodium Knowlesi

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Journal Infect Immun
Date 1989 Oct 1
PMID 2777381
Citations 22
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Abstract

We used immunoelectron microscopy to study the fate of dense granules during the invasion of erythrocytes by Plasmodium knowlesi merozoites. When merozoites entered host cells, dense granules moved to the pellicle, released their contents into the parasitophorous vacuole space, and then moved into fingerlike channels of the vacuole membrane. This is the first report showing that the content of dense granules of P. knowlesi is different from the contents of rhoptries and micronemes and is associated with the formation of channels from the parasitophorous vacuole.

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References
1.
Ladda R, Aikawa M, SPRINZ H . Penetration of erythrocytes by merozoites of mammalian and avian malarial parasites. J Parasitol. 1969; 55(3):633-44. View

2.
Bannister L, Butcher G, Dennis E, Mitchell G . Structure and invasive behaviour of Plasmodium knowlesi merozoites in vitro. Parasitology. 1975; 71(3):483-91. DOI: 10.1017/s0031182000047247. View

3.
MILLER L, POWERS K, Shiroishi T . Plasmodium knowlesi: functional immunity and antimerozoite antibodies in rhesus monkeys after repeated infection. Exp Parasitol. 1977; 41(1):105-11. DOI: 10.1016/0014-4894(77)90135-7. View

4.
Aikawa M, MILLER L, Johnson J, Rabbege J . Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite. J Cell Biol. 1978; 77(1):72-82. PMC: 2110026. DOI: 10.1083/jcb.77.1.72. View

5.
Young R, Davis R . Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A. 1983; 80(5):1194-8. PMC: 393560. DOI: 10.1073/pnas.80.5.1194. View