Correlation Between Intraocular Pressure and Central Corneal Thickness in Persian Children

Overview

Journal Ophthalmol Ther

Specialty Ophthalmology

Date 2016 Oct 7

PMID 27709441

Citations 10

Authors

Mahmood Nejabat

Fatemeh Heidary

Mohammad Reza Talebnejad

Ramin Salouti

Mohammad Hossein Nowroozzadeh

Masoumeh Masoumpour

Hamideh Mahdaviazad

Zahra Tajbakhsh

Maryam Keshtkar

Hossein Jamali

Mohammad Reza Khalili

Hossein Movahedan

Narges Roustaei

Reza Gharebaghi

Affiliations

Soon will be listed here.

Abstract

Introduction: This study aimed to determine intraocular pressure (IOP) and central corneal thickness (CCT) measurements in healthy Persian children to find clinical reference values in this ethnicity. Additionally, we examined the possible relationship between these measurements.

Methods: This cross-sectional study included 262 eyes of 131 Persian primary school children between 6 and 13 years of age. All eyes were healthy and had no anterior or posterior segment abnormalities, corneal disease, or evidence of glaucoma. Specular microscopy was used to measure CCT and both noncontact tonometry (NCT) and Goldmann applanation tonometer (GAT) were used to measure IOP. Correlations between IOP measurements were also examined.

Results: Mean CCT was 513.47 ± 34.51 μm in the right eye (OD) and 513.93 ± 33.88 μm in the left eye (OS). The CCT was not significantly different between older (10-13 years) and younger (6-9 years) patients. Mean IOP measured with GAT was 13.86 ± 2.13 mmHg OD and 13.72 ± 2.04 mmHg OS and mean IOP measured with NCT was 15.26 ± 2.38 mmHg OD and 15.11 ± 2.18 mmHg OS. The IOP and CCT measured with GAT were weakly correlated (OD: r = 0.141, P = 0.114; OS: r = 0.236, P = 0.007). However, IOP and CCT measured with NCT (OD: r = 0.487, P = 0.000; OS: r = 0.456, P = 0.000) were moderately correlated. Our outcomes demonstrated that for 100 μm increase in CCT, IOP measured with GAT and NCT increased by 0.8 and 3.3 mmHg, respectively, in OD and by 1.4 and 2.9 mmHg in OS. Based on intraclass correlation coefficients, IOP measurements made with GAT and NCT were in fair agreement in OD and in good agreement in OS.

Conclusion: The IOP and CCT in healthy Persian school children (6-13 years old) were positively correlated. Our findings revealed that corneal thickness is thinner in Persian children than in most other racial groups.

Funding: This study has been funded by deputy dean in research of School of Medicine and deputy vice chancellor of Shiraz University of Medical Sciences, Shiraz, Iran.

Citing Articles

Exploring the Link Between Intraocular Pressure and Central Corneal Thickness, as Well as the Diurnal Variation of Intraocular Pressure, in the Elderly Population of North Karnataka.

Mudhol R, Sneha L Cureus. 2024; 16(7):e64022.

PMID: 39109137 PMC: 11302409. DOI: 10.7759/cureus.64022.

Distribution and analysis of intraocular pressure and its possible association with glaucoma in children.

Han F, Li J, Zhao X, Li X, Wei P, Wang Y Int Ophthalmol. 2021; 41(8):2817-2825.

PMID: 33842987 DOI: 10.1007/s10792-021-01838-6.

Author's Reply.

Talebnejad M, Nowroozzadeh M, Mahdaviazad H J Ophthalmic Vis Res. 2020; 15(1):125.

PMID: 32095223 PMC: 7001016. DOI: 10.18502/jovr.v15i1.5970.

Prevalence of Visual Impairment in School Children.

Gharebaghi R, Heidary F J Ophthalmic Vis Res. 2020; 15(1):123-124.

PMID: 32095222 PMC: 7001027. DOI: 10.18502/jovr.v15i1.5968.

Distribution of corneal thickness and its determinants in 6-12-year-old children in an Iranian general population.

Hashemi H, Saatchi M, Khabazkhoob M, Emamian M, Yekta A, Fotouhi A J Curr Ophthalmol. 2019; 31(2):150-156.

PMID: 31317092 PMC: 6611839. DOI: 10.1016/j.joco.2017.12.001.

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