Influence of the First Consultation on Adherence to Antiretroviral Therapy for HIV-infected Patients

Overview

Journal Open AIDS J

Publisher Bentham Open

Specialty Infectious Diseases

Date 2016 Oct 7

PMID 27708747

Citations 4

Authors

Marion Peyre

Aurelie Gauchet

Matthieu Roustit

Pascale Leclercq

Olivier Epaulard

Affiliations

Soon will be listed here.

Abstract

Background: Physician attitude influences the way patients cope with diagnosis and therapy in chronic severe diseases such as cancer. Previous studies showed that such an effect exists in HIV care; it is likely that it begins with the first contact with a physician.

Objective: We aimed to explore in HIV-infected persons their perception of the first consultation they had with an HIV specialist (PFC-H), and whether this perception correlates with adherence to antiretroviral therapy.

Method: The study was conducted in Grenoble University Hospital, France, a tertiary care center. Every antiretroviral-experienced patient was asked to freely complete a self-reported, anonymous questionnaire concerning retrospective PFC-H, present adherence (Morisky scale), and present perceptions and beliefs about medicine (BMQ scale).

Results: One hundred and fifty-one questionnaires were available for evaluation. PFC-H score and adherence were correlated, independently from age, gender, and numbers of pill(s) and of pill intake(s) per day. BMQ score also correlated with adherence; structural equation analysis suggested that the effect of PFC-H on adherence is mediated by positive beliefs.

Conclusion: These results suggest that for HIV-infected persons, the perceptions remaining from the first consultation with an HIV specialist physician influence important issues such as adherence and perception about medicine. Physicians must be aware of this potentially long-lasting effect.

Citing Articles

Structural Equation Modelling to Identify Psychometric Determinants of Medication Adherence in a Survey of Kidney Dialysis Patients.

Marshall M, Curd S, Kennedy J, Khatri D, Lee S, Pireva K Patient Prefer Adherence. 2024; 18:855-878.

PMID: 38645697 PMC: 11032681. DOI: 10.2147/PPA.S454248.

Necessity and concerns beliefs and HIV medication adherence: a systematic review.

Mitzel L, Vanable P J Behav Med. 2019; 43(1):1-15.

PMID: 31396819 DOI: 10.1007/s10865-019-00089-2.

In Women's Eyes: Key Barriers to Women's Access to HIV Treatment and a Rights-Based Approach to their Sustained Well-Being.

Orza L, Bass E, Bell E, Crone E, Damji N, Dilmitis S Health Hum Rights. 2018; 19(2):155-168.

PMID: 29302173 PMC: 5739367.

Ask women living with HIV what's needed to achieve safe pregnancies in serodifferent relationships.

Orza L, Bewley S, Crone E, Mworeko L, Namiba A, Otieno T J Int AIDS Soc. 2017; 20(Suppl 1):21469.

PMID: 28361504 PMC: 5577728. DOI: 10.7448/IAS.20.2.21469.

References

Hinkin C, Castellon S, Durvasula R, Hardy D, Lam M, Mason K . Medication adherence among HIV+ adults: effects of cognitive dysfunction and regimen complexity. Neurology. 2002; 59(12):1944-50. PMC: 2871670. DOI: 10.1212/01.wnl.0000038347.48137.67. View

Furber L, Bonas S, Murtagh G, Thomas A . Patients' experiences of an initial consultation in oncology: knowing and not knowing. Br J Health Psychol. 2014; 20(2):261-73. DOI: 10.1111/bjhp.12096. View

Perez-Salgado D, Compean-Dardon M, Staines-Orozco M, Ortiz-Hernandez L . Satisfaction with Healthcare Services and Adherence to Antiretroviral Therapy among Patients with HIV Attending Two Public Institutions. Rev Invest Clin. 2015; 67(2):80-8. View

Wilson S, Sikkema K, Ranby K . Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse. AIDS Care. 2014; 26(8):959-67. PMC: 4156823. DOI: 10.1080/09540121.2013.873765. View

Al-Dakkak I, Patel S, McCann E, Gadkari A, Prajapati G, Maiese E . The impact of specific HIV treatment-related adverse events on adherence to antiretroviral therapy: a systematic review and meta-analysis. AIDS Care. 2012; 25(4):400-14. PMC: 3613968. DOI: 10.1080/09540121.2012.712667. View

Barnabas R, van Rooyen H, Tumwesigye E, Murnane P, Baeten J, Humphries H . Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study. Lancet HIV. 2015; 1(2):e68-e76. PMC: 4292844. DOI: 10.1016/S2352-3018(14)70024-4. View

Linetzky B, Jiang D, Funnell M, Curtis B, Polonsky W . Exploring the role of the patient-physician relationship on insulin adherence and clinical outcomes in type 2 diabetes: Insights from the MOSAIc study. J Diabetes. 2016; 9(6):596-605. DOI: 10.1111/1753-0407.12443. View

Laws M, Rose G, Bezreh T, Beach M, Taubin T, Kogelman L . Treatment acceptance and adherence in HIV disease: patient identity and the perceived impact of physician-patient communication. Patient Prefer Adherence. 2012; 6:893-903. PMC: 3526886. DOI: 10.2147/PPA.S36912. View

Schneider J, Kaplan S, Greenfield S, Li W, Wilson I . Better physician-patient relationships are associated with higher reported adherence to antiretroviral therapy in patients with HIV infection. J Gen Intern Med. 2004; 19(11):1096-103. PMC: 1494791. DOI: 10.1111/j.1525-1497.2004.30418.x. View

10.

Ti L, Milloy M, Shannon K, Simo A, Hogg R, Guillemi S . Suboptimal plasma HIV-1 RNA suppression and adherence among sex workers who use illicit drugs in a Canadian setting: an observational cohort study. Sex Transm Infect. 2014; 90(5):418-22. PMC: 4102614. DOI: 10.1136/sextrans-2013-051408. View

11.

Magidson J, Saal W, Nel A, Remmert J, Kagee A . Relationship between depressive symptoms, alcohol use, and antiretroviral therapy adherence among HIV-infected, clinic-attending patients in South Africa. J Health Psychol. 2016; 22(11):1426-1433. PMC: 4985498. DOI: 10.1177/1359105316628743. View

12.

Besson C, Rannou S, Elmaaroufi H, Guirimand N, Tresvaux du Fraval F, Cartron L . Disclosure of myelodysplastic syndrome diagnosis: improving patients' understanding and experience. Eur J Haematol. 2012; 90(2):151-6. DOI: 10.1111/ejh.12048. View

13.

Gabrijel S, Grize L, Helfenstein E, Brutsche M, Grossman P, Tamm M . Receiving the diagnosis of lung cancer: patient recall of information and satisfaction with physician communication. J Clin Oncol. 2008; 26(2):297-302. DOI: 10.1200/JCO.2007.13.0609. View

14.

Walling A, Lorenz K, Dy S, Naeim A, Sanati H, Asch S . Evidence-based recommendations for information and care planning in cancer care. J Clin Oncol. 2008; 26(23):3896-902. DOI: 10.1200/JCO.2007.15.9509. View

15.

Berg K, Demas P, Howard A, Schoenbaum E, Gourevitch M, Arnsten J . Gender differences in factors associated with adherence to antiretroviral therapy. J Gen Intern Med. 2004; 19(11):1111-7. PMC: 1196356. DOI: 10.1111/j.1525-1497.2004.30445.x. View

16.

Fujimori M, Shirai Y, Asai M, Kubota K, Katsumata N, Uchitomi Y . Effect of communication skills training program for oncologists based on patient preferences for communication when receiving bad news: a randomized controlled trial. J Clin Oncol. 2014; 32(20):2166-72. DOI: 10.1200/JCO.2013.51.2756. View

17.

Gauchet A, Tarquinio C, Fischer G . Psychosocial predictors of medication adherence among persons living with HIV. Int J Behav Med. 2007; 14(3):141-50. DOI: 10.1007/BF03000185. View

18.

Tiyou A, Belachew T, Alemseged F, Biadgilign S . Predictors of adherence to antiretroviral therapy among people living with HIV/AIDS in resource-limited setting of southwest ethiopia. AIDS Res Ther. 2010; 7:39. PMC: 2988692. DOI: 10.1186/1742-6405-7-39. View

19.

Schiattino I, Villegas R, Cruzat A, Cuenca J, Salazar L, Aravena O . Multiple imputation procedures allow the rescue of missing data: an application to determine serum tumor necrosis factor (TNF) concentration values during the treatment of rheumatoid arthritis patients with anti-TNF therapy. Biol Res. 2005; 38(1):7-12. DOI: 10.4067/s0716-97602005000100002. View

20.

Bianco J, Heckman T, Sutton M, Watakakosol R, Lovejoy T . Predicting adherence to antiretroviral therapy in HIV-infected older adults: the moderating role of gender. AIDS Behav. 2010; 15(7):1437-46. DOI: 10.1007/s10461-010-9756-2. View