Psychosocial Influences on Acceptability and Feasibility of Salivary Cortisol Collection From Community Samples of Children

Overview

Journal Res Nurs Health

Specialties Health Services
Nursing
Public Health

Date 2016 Oct 1

PMID 27686043

Citations 5

Authors

Eileen M Condon

Affiliations

Soon will be listed here.

Abstract

Salivary cortisol is considered to be a safe and noninvasive measure of hypothalamic-pituitary-adrenal axis functioning, and is a commonly measured biomarker of the human stress response in pediatric research. However, cortisol is highly variable and sensitive to a wide range of factors, creating a challenge for reliable salivary cortisol collection in the community setting. Furthermore, the acceptability of salivary cortisol collection in community samples of children is largely unknown. The purpose of this integrative review was to investigate current evidence on the acceptability and feasibility of salivary cortisol collection in community samples of children. In an analysis framed by the Theory of Planned Behavior, data extracted from 31 studies revealed six categories of psychosocial influences on acceptability and feasibility: uncertainty and misconceptions, cultural and ethnic values, family rules and values, difficulty following protocols and procedures, burden of multiple samples, and child refusal or resistance. Further research is required to fully understand the factors that influence acceptability and feasibility of salivary cortisol collection in community samples of children. Understanding individual, family, and community perceptions of biobehavioral research will lead to more culturally sensitive and feasible community-based research methods. © 2016 Wiley Periodicals, Inc.

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References

Groschl M, Rauh M . Influence of commercial collection devices for saliva on the reliability of salivary steroids analysis. Steroids. 2006; 71(13-14):1097-100. DOI: 10.1016/j.steroids.2006.09.007. View

Hiremath G, Olive A, Shah S, Davis C, Shulman R, Devaraj S . Comparing methods to collect saliva from children to analyze cytokines related to allergic inflammation. Ann Allergy Asthma Immunol. 2014; 114(1):63-4. PMC: 4307382. DOI: 10.1016/j.anai.2014.09.012. View

Laurent H, Gilliam K, Bruce J, Fisher P . HPA stability for children in foster care: mental health implications and moderation by early intervention. Dev Psychobiol. 2014; 56(6):1406-15. PMC: 4415368. DOI: 10.1002/dev.21226. View

Stalder T, Baumler D, Miller R, Alexander N, Kliegel M, Kirschbaum C . The cortisol awakening response in infants: ontogeny and associations with development-related variables. Psychoneuroendocrinology. 2012; 38(4):552-9. DOI: 10.1016/j.psyneuen.2012.07.015. View

Bakken S, Reame N . The Promise and Potential Perils of Big Data for Advancing Symptom Management Research in Populations at Risk for Health Disparities. Annu Rev Nurs Res. 2015; 34:247-60. DOI: 10.1891/0739-6686.34.247. View

Adam E, Kumari M . Assessing salivary cortisol in large-scale, epidemiological research. Psychoneuroendocrinology. 2009; 34(10):1423-36. DOI: 10.1016/j.psyneuen.2009.06.011. View

Egliston K, McMahon C, Austin M . Stress in pregnancy and infant HPA axis function: conceptual and methodological issues relating to the use of salivary cortisol as an outcome measure. Psychoneuroendocrinology. 2006; 32(1):1-13. DOI: 10.1016/j.psyneuen.2006.10.003. View

Watamura S, Coe C, Laudenslager M, Robertson S . Child care setting affects salivary cortisol and antibody secretion in young children. Psychoneuroendocrinology. 2010; 35(8):1156-66. DOI: 10.1016/j.psyneuen.2010.02.001. View

Kaitz M, Sabato R, Shalev I, Ebstein R, Mankuta D . Children's noncompliance during saliva collection predicts measures of salivary cortisol. Dev Psychobiol. 2011; 54(2):113-23. DOI: 10.1002/dev.20580. View

10.

Cicchetti D, Gunnar M . Integrating biological measures into the design and evaluation of preventive interventions. Dev Psychopathol. 2008; 20(3):737-43. DOI: 10.1017/S0954579408000357. View

11.

Kudielka B, Gierens A, Hellhammer D, Wust S, Schlotz W . Salivary cortisol in ambulatory assessment--some dos, some don'ts, and some open questions. Psychosom Med. 2012; 74(4):418-31. DOI: 10.1097/PSY.0b013e31825434c7. View

12.

Corbie-Smith G, Thomas S, St George D . Distrust, race, and research. Arch Intern Med. 2002; 162(21):2458-63. DOI: 10.1001/archinte.162.21.2458. View

13.

Harmon A, Hibel L, Rumyantseva O, Granger D . Measuring salivary cortisol in studies of child development: watch out--what goes in may not come out of saliva collection devices. Dev Psychobiol. 2007; 49(5):495-500. DOI: 10.1002/dev.20231. View

14.

Sondeijker F, Ferdinand R, Oldehinkel A, Tiemeier H, Ormel J, Verhulst F . HPA-axis activity as a predictor of future disruptive behaviors in young adolescents. Psychophysiology. 2008; 45(3):398-404. DOI: 10.1111/j.1469-8986.2008.00639.x. View

15.

Hanrahan K, McCarthy A, Kleiber C, Lutgendorf S, Tsalikian E . Strategies for salivary cortisol collection and analysis in research with children. Appl Nurs Res. 2006; 19(2):95-101. DOI: 10.1016/j.apnr.2006.02.001. View

16.

Granger D, Kivlighan K, Fortunato C, Harmon A, Hibel L, Schwartz E . Integration of salivary biomarkers into developmental and behaviorally-oriented research: problems and solutions for collecting specimens. Physiol Behav. 2007; 92(4):583-90. DOI: 10.1016/j.physbeh.2007.05.004. View

17.

Dietrich A, Ormel J, Buitelaar J, Verhulst F, Hoekstra P, Hartman C . Cortisol in the morning and dimensions of anxiety, depression, and aggression in children from a general population and clinic-referred cohort: An integrated analysis. The TRAILS study. Psychoneuroendocrinology. 2012; 38(8):1281-98. DOI: 10.1016/j.psyneuen.2012.11.013. View

18.

Boulware L, Cooper L, Ratner L, LaVeist T, Powe N . Race and trust in the health care system. Public Health Rep. 2003; 118(4):358-65. PMC: 1497554. DOI: 10.1093/phr/118.4.358. View

19.

Saridjan N, Huizink A, Koetsier J, Jaddoe V, Mackenbach J, Hofman A . Do social disadvantage and early family adversity affect the diurnal cortisol rhythm in infants? The Generation R Study. Horm Behav. 2009; 57(2):247-54. DOI: 10.1016/j.yhbeh.2009.12.001. View

20.

Gutteling B, de Weerth C, Buitelaar J . Prenatal stress and children's cortisol reaction to the first day of school. Psychoneuroendocrinology. 2005; 30(6):541-9. DOI: 10.1016/j.psyneuen.2005.01.002. View