Metastatic Sebaceous Cell Carcinoma, Review of the Literature and Use of Electrochemotherapy As Possible New Treatment Modality

Overview

Journal Radiol Oncol

Publisher Sciendo

Specialties Oncology
Radiology

Date 2016 Sep 29

PMID 27679547

Citations 4

Authors

Simone Ribero

Eugenio Sportoletti Baduel

Matteo Brizio

Franco Picciotto

Emi Dika

Maria Teresa Fierro

Giuseppe Macripo

Pietro Quaglino

Affiliations

Soon will be listed here.

Abstract

Background: Metastatic extraorbital sebaceous carcinoma is a rare event that could involve the head and neck. The treatment of choice for the initial stage of the disease is surgery and/or radiotherapy. The treatment of recurrent or advanced disease is still controversial.

Material And Methods: Extensive literature search was done, and the treatment options are discussed.

Results: Results. The literature search found several treatment modalities in use for the treatment of metastatic extraorbital sebaceous carcinoma. Electrochemotherapy was not included in the reported treatments. We used this technique for a man of 85 years old with a recurrent and locally metastatic extraorbital sebaceous carcinoma of the scalp. During the period of 8 months, two sessions of electrochemotherapy were employed, which resulted in an objective response of the tumour and good quality of life.

Conclusions: Electrochemotherapy has shown to be a interesting tools for treatment of metastatic extraorbital sebaceous carcinoma when other radical options are not available or convenient.

Citing Articles

Sebaceous breast carcinoma.

de Alencar N, de Souza D, Lourenco A, Silva R Autops Case Rep. 2022; 12:e2021365.

PMID: 35496738 PMC: 9037860. DOI: 10.4322/acr.2021.365.

Aggressive sebaceous carcinoma of the scalp: a case report and literature review.

Li G, Shen J, Huang H, Chen R, Zhou G Transl Cancer Res. 2022; 10(9):4237-4242.

PMID: 35116719 PMC: 8798961. DOI: 10.21037/tcr-20-3443.

[Management of malignant adnexal neoplasms of the skin].

Nagel P, Muller V, Utikal J Hautarzt. 2021; 72(7):619-632.

PMID: 34137901 DOI: 10.1007/s00105-021-04829-x.

Sebaceous Carcinoma: A Review of the Scientific Literature.

Knackstedt T, Samie F Curr Treat Options Oncol. 2017; 18(8):47.

PMID: 28681210 DOI: 10.1007/s11864-017-0490-0.

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