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Questionnaire Survey Regarding the Current Status of Super-extended Lymph Node Dissection in Japan

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Date 2016 Sep 28
PMID 27672429
Citations 3
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Abstract

Aim: To verify the current status of super-extended lymph node dissection for advanced gastric cancer according to a questionnaire survey.

Methods: One-hundred and five institutions responded to the questionnaire. The survey included the following items: Number of experiences, whether performed prophylactically and/or therapeutically, whether preoperative chemotherapy was provided, number of preoperative chemotherapy rounds, and therapeutic options after chemotherapy.

Results: Eighty-seven of the 105 institutions (83%) had performed D3 gastrectomy in the past or continued to perform D3 gastrectomy at present. However, D3 gastrectomy was rarely performed prophylactically in clinical practice. Seventy-eight institutions (74%) indicated that preoperative chemotherapy with curative intent was required for patients suspected of having para-aortic node (PAN) metastases. After chemotherapy, a D3 gastrectomy was scheduled for patients with a complete or partial response, stable disease, and progressive disease at 36 (46%), 28 (36%), and 13 (17%) of the institutions, respectively.

Conclusion: For patients with apparent PAN metastasis, a D3 gastrectomy is typically planned if a few courses of preoperative chemotherapy yield at least a stable disease condition.

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References
1.
Ajani J, Ota D, Jessup J, Ames F, McBride C, Boddie A . Resectable gastric carcinoma. An evaluation of preoperative and postoperative chemotherapy. Cancer. 1991; 68(7):1501-6. DOI: 10.1002/1097-0142(19911001)68:7<1501::aid-cncr2820680706>3.0.co;2-l. View

2.
Leichman L, SILBERMAN H, Leichman C, Spears C, Ray M, Muggia F . Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program. J Clin Oncol. 1992; 10(12):1933-42. DOI: 10.1200/JCO.1992.10.12.1933. View

3.
Tsuburaya A, Mizusawa J, Tanaka Y, Fukushima N, Nashimoto A, Sasako M . Neoadjuvant chemotherapy with S-1 and cisplatin followed by D2 gastrectomy with para-aortic lymph node dissection for gastric cancer with extensive lymph node metastasis. Br J Surg. 2014; 101(6):653-60. DOI: 10.1002/bjs.9484. View

4.
Lee W, Lee P, Yue S, Chang K, Wei T, Chen K . Lymph node metastases in gastric cancer: significance of positive number. Oncology. 1995; 52(1):45-50. DOI: 10.1159/000227426. View

5.
Hartgrink H, van de Velde C, Putter H, Songun I, Tesselaar M, Kranenbarg E . Neo-adjuvant chemotherapy for operable gastric cancer: long term results of the Dutch randomised FAMTX trial. Eur J Surg Oncol. 2004; 30(6):643-9. DOI: 10.1016/j.ejso.2004.04.013. View