Autoimmune Gastritis

Overview

Journal Wien Med Wochenschr

Specialty General Medicine

Date 2016 Sep 28

PMID 27671008

Citations 30

Authors

Stefanie Kulnigg-Dabsch

Affiliations

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Abstract

Autoimmune gastritis is a chronic inflammatory disease with destruction of parietal cells of the corpus and fundus of the stomach. The known consequence is vitamin B12 deficiency and, consequently, pernicious anemia. However, loss of parietal cells reduces secretion of gastric acid which is also required for absorption of inorganic iron; thus, iron deficiency is commonly found in patients with autoimmune gastritis. This usually precedes vitamin B12 deficiency and is found mainly in young women. Patients with chronic iron deficiency, especially those refractory to oral iron therapy, should therefore be evaluated for the presence of autoimmune gastritis.

Citing Articles

Endoscopic and clinical characteristics of autoimmune atrophic gastritis: Retrospective study.

Khalaf K, Fujiyoshi Y, Bechara R Endosc Int Open. 2025; 13:a24774666.

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Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function.

Panozzo M, Antico A, Bizzaro N J Transl Autoimmun. 2025; 10:100273.

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Unraveling the Mysteries of Autoimmune Gastritis.

Soykan I, Er R, Baykara Y, Kalkan C Turk J Gastroenterol. 2024; .

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Vitamin B Metabolism: A Network of Multi-Protein Mediated Processes.

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Unveiling early stage autoimmune gastritis: novel endoscopic insights from two case reports.

Yu Y, Shangguan X, Yu R, Wu Y, Xu E, Tan C Front Immunol. 2024; 15:1416292.

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