Eukaryotic Transcription Initiation Machinery Visualized at Molecular Level

Overview

Journal Transcription

Specialty Molecular Biology

Date 2016 Sep 23

PMID 27658022

Citations 3

Authors

Yan Han

Yuan He

Affiliations

Soon will be listed here.

Abstract

The structures of RNA Polymerase (Pol) II pre-initiation complexes (PIC) have recently been determined at near-atomic resolution, elucidating unprecedented mechanistic details of promoter opening during transcription initiation. The key structural features of promoter opening are summarized here. Structural knowledge of Pol I and III PIC is also briefly discussed.

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