Pulmonary Hypertension Imitating HELLP Syndrome

Overview

Journal Obstet Med

Specialty Gynecology & Obstetrics

Date 2016 Sep 23

PMID 27656251

Citations 1

Authors

Adam Morton

Affiliations

Soon will be listed here.

Abstract

A case of undiagnosed pulmonary hypertension in a woman with mixed connective tissue disease presenting with microangiopathic haemolysis, thrombocytopenia and elevated liver enzymes imitating severe preeclampsia (HELLP syndrome) is described. Connective tissue disorders are associated with an increased prevalence of pulmonary hypertension. Maternal mortality rates with pulmonary hypertension in pregnancy are extremely high. All women with connective tissue disorders should have pulmonary hypertension excluded by echocardiography before attempting conception. End-stage pulmonary hypertension may be associated with haemolysis and thrombocytopenia and thus may imitate severe preeclampsia in pregnant women. There may be a role for extracorporeal membrane oxygenation in the peripartum management of women with severe pulmonary hypertension.

Citing Articles

Mixed connective tissue disease in pregnancy: A case series and systematic literature review.

Tardif M, Mahone M Obstet Med. 2019; 12(1):31-37.

PMID: 30891090 PMC: 6416686. DOI: 10.1177/1753495X18793484.

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