Comprehensive Genome Scale Phylogenetic Study Provides New Insights on the Global Expansion of Chikungunya Virus

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2016 Sep 23

PMID 27654297

Citations 49

Authors

Rubing Chen

Vinita Puri

Nadia Fedorova

David Lin

Kumar L Hari

Ravi Jain

Juan David Rodas

Suman R Das

Reed S Shabman

Scott C Weaver

Affiliations

Soon will be listed here.

Abstract

Importance: Chikungunya fever is a reemerging infectious disease that is transmitted by Aedes mosquitoes and causes severe health and economic burdens in affected populations. Since the unprecedented Indian Ocean and Indian subcontinent outbreaks of 2005 and 2006, CHIKV has further expanded its geographic range, including to the Americas in 2013. Its evolution and transmission during and following these epidemics, as well as the recent evolution and spread of other lineages, require optimal assessment. Using newly obtained genome sequences, we provide a comprehensive update of the global distribution of CHIKV genetic diversity and analyze factors associated with recent outbreaks. These results provide a solid foundation for future evolutionary studies of CHIKV that can elucidate emergence mechanisms and also may help to predict future epidemics.

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References

Djikeng A, Halpin R, Kuzmickas R, DePasse J, Feldblyum J, Sengamalay N . Viral genome sequencing by random priming methods. BMC Genomics. 2008; 9:5. PMC: 2254600. DOI: 10.1186/1471-2164-9-5. View

AbuBakar S, Sam I, Wong P, MatRahim N, Hooi P, Roslan N . Reemergence of endemic Chikungunya, Malaysia. Emerg Infect Dis. 2007; 13(1):147-9. PMC: 2725805. DOI: 10.3201/eid1301.060617. View

Powers A, Brault A, Tesh R, Weaver S . Re-emergence of Chikungunya and O'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships. J Gen Virol. 2000; 81(Pt 2):471-9. DOI: 10.1099/0022-1317-81-2-471. View

Weaver S, Costa F, Garcia-Blanco M, Ko A, Ribeiro G, Saade G . Zika virus: History, emergence, biology, and prospects for control. Antiviral Res. 2016; 130:69-80. PMC: 4851879. DOI: 10.1016/j.antiviral.2016.03.010. View

Galatas B, Ly S, Duong V, Baisley K, Nguon K, Chan S . Long-Lasting Immune Protection and Other Epidemiological Findings after Chikungunya Emergence in a Cambodian Rural Community, April 2012. PLoS Negl Trop Dis. 2016; 10(1):e0004281. PMC: 4713465. DOI: 10.1371/journal.pntd.0004281. View

Maha M, Susilarini N, Hariastuti N . Chikungunya virus mutation, Indonesia, 2011. Emerg Infect Dis. 2015; 21(2):379-81. PMC: 4313651. DOI: 10.3201/eid2102.141121. View

Weaver S, Lecuit M . Chikungunya virus and the global spread of a mosquito-borne disease. N Engl J Med. 2015; 372(13):1231-9. DOI: 10.1056/NEJMra1406035. View

Parashar D, Amdekar S, More A, Patil P, More R, Babu V . Chikungunya fever outbreak in Guntur, Andhra Pradesh, India. Indian J Med Res. 2016; 142 Suppl:S111-5. PMC: 4795341. DOI: 10.4103/0971-5916.176639. View

Angelini R, Finarelli A, Angelini P, Po C, Petropulacos K, Macini P . An outbreak of chikungunya fever in the province of Ravenna, Italy. Euro Surveill. 2007; 12(9):E070906.1. DOI: 10.2807/esw.12.36.03260-en. View

10.

Diaz-Gonzalez E, Kautz T, Dorantes-Delgado A, Malo-Garcia I, Laguna-Aguilar M, Langsjoen R . First Report of Aedes aegypti Transmission of Chikungunya Virus in the Americas. Am J Trop Med Hyg. 2015; 93(6):1325-9. PMC: 4674253. DOI: 10.4269/ajtmh.15-0450. View

11.

Hasebe F, Parquet M, Pandey B, Mathenge E, Morita K, Balasubramaniam V . Combined detection and genotyping of Chikungunya virus by a specific reverse transcription-polymerase chain reaction. J Med Virol. 2002; 67(3):370-4. DOI: 10.1002/jmv.10085. View

12.

Peyrefitte C, Rousset D, Pastorino B, Pouillot R, Bessaud M, Tock F . Chikungunya virus, Cameroon, 2006. Emerg Infect Dis. 2007; 13(5):768-71. PMC: 2738435. DOI: 10.3201/eid1305.061500. View

13.

Mattar S, Miranda J, Pinzon H, Tique V, Bolanos A, Aponte J . Outbreak of Chikungunya virus in the north Caribbean area of Colombia: clinical presentation and phylogenetic analysis. J Infect Dev Ctries. 2015; 9(10):1126-32. DOI: 10.3855/jidc.6670. View

14.

Leparc-Goffart I, Nougairede A, Cassadou S, Prat C, de Lamballerie X . Chikungunya in the Americas. Lancet. 2014; 383(9916):514. DOI: 10.1016/S0140-6736(14)60185-9. View

15.

Diallo M, Thonnon J, Traore-Lamizana M, Fontenille D . Vectors of Chikungunya virus in Senegal: current data and transmission cycles. Am J Trop Med Hyg. 1999; 60(2):281-6. DOI: 10.4269/ajtmh.1999.60.281. View

16.

Panning M, Grywna K, Van Esbroeck M, Emmerich P, Drosten C . Chikungunya fever in travelers returning to Europe from the Indian Ocean region, 2006. Emerg Infect Dis. 2008; 14(3):416-22. PMC: 2570846. DOI: 10.3201/eid1403.070906. View

17.

Moyen N, Thiberville S, Pastorino B, Nougairede A, Thirion L, Mombouli J . First reported chikungunya fever outbreak in the republic of Congo, 2011. PLoS One. 2014; 9(12):e115938. PMC: 4277398. DOI: 10.1371/journal.pone.0115938. View

18.

Kaariainen L, Ahola T . Functions of alphavirus nonstructural proteins in RNA replication. Prog Nucleic Acid Res Mol Biol. 2002; 71:187-222. PMC: 7133189. DOI: 10.1016/s0079-6603(02)71044-1. View

19.

Ho S, Duchene S . Molecular-clock methods for estimating evolutionary rates and timescales. Mol Ecol. 2014; 23(24):5947-65. DOI: 10.1111/mec.12953. View

20.

Chen R, Vasilakis N . Dengue--quo tu et quo vadis?. Viruses. 2011; 3(9):1562-608. PMC: 3187692. DOI: 10.3390/v3091562. View