Vaccines and Multiple Sclerosis: a Systematic Review

Overview

Journal J Neurol

Specialty Neurology

Date 2016 Sep 9

PMID 27604618

Citations 67

Authors

Mia Topsoe Mailand

Jette Lautrup Frederiksen

Affiliations

Soon will be listed here.

Abstract

Vaccinations are often the most effective tool against some disease known to mankind. This study offers a literature review on the role of vaccines regarding the risk of developing multiple sclerosis (MS) and MS relapse. The method used in this study is a systematic literature review on the database PubMed. The study found no change in risk of developing multiple sclerosis (MS) after vaccination against hepatitis B virus, human papillomavirus, seasonal influenza, measles-mumps-rubella, variola, tetanus, Bacillus Calmette-Guérin (BCG), polio, or diphtheria. No change in risk of relapse was found for influenza. Further research is needed for the potential therapeutic use of the BCG vaccine in patients in risk of developing MS and for the preventive potential of the tetanus and diphtheria vaccine.

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