Cranial Magnetic Resonance Imaging in Elderly American Indians: Design, Methods, and Implementation of the Cerebrovascular Disease and Its Consequences in American Indians Study

Overview

Journal Neuroepidemiology

Specialties Neurology
Public Health

Date 2016 Sep 8

PMID 27603047

Citations 29

Authors

Astrid M Suchy-Dicey

Dean Shibata

Lyle G Best

Steven P Verney

William T Longstreth Jr

Elisa T Lee

Peter M Okin

Richard Devereux

Marcia OLeary

Tauqeer Ali

Paul N Jensen

Clemma Muller

Lonnie A Nelson

Everett Rhoades

Tara Madhyastha

Thomas J Grabowski

Norman Beauchamp

Jason G Umans

Dedra Buchwald

Affiliations

Soon will be listed here.

Abstract

The Cerebrovascular Disease and its Consequences in American Indians (CDCAI) Study recruited surviving members of a 20-year, longitudinal, population-based cohort of American Indians focused on cardiovascular disease, its risk factors, and its consequences. The goal of the CDCAI Study is to characterize the burden, risk factors, and manifestations of vascular brain injury identified on cranial MRI. The CDCAI Study investigators enrolled 1,033 participants aged 60 and older from 11 American Indian communities and tribes in the Northern Plains, Southern Plains, and Southwestern United States. In addition to cranial MRI performed according to standardized protocols, participants underwent extensive medical interview, clinical examination, neurocognitive testing, physical function evaluation, electrocardiogram, and provided blood and urine specimens. Participants also self-administered questionnaires covering demographics, quality of life, and medical history. This report describes the design, implementation, and some of the unique challenges of this study and data collection.

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