Signaling a Link Between Interferon and the Traits of Down Syndrome
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Abstract
Elevated interferon signaling is a hallmark of Down syndrome.
Citing Articles
JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.
Tuttle K, Waugh K, Araya P, Minter R, Orlicky D, Ludwig M Cell Rep. 2020; 33(7):108407.
PMID: 33207208 PMC: 7727402. DOI: 10.1016/j.celrep.2020.108407.
Guedj F, Siegel A, Pennings J, Alsebaa F, Massingham L, Tantravahi U Am J Hum Genet. 2020; 107(5):911-931.
PMID: 33098770 PMC: 7675036. DOI: 10.1016/j.ajhg.2020.10.001.
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