Visualizing Herpesvirus Procapsids in Living Cells

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2016 Sep 2

PMID 27581983

Citations 5

Authors

Oana Maier

Patricia J Sollars

Gary E Pickard

Gregory A Smith

Affiliations

Soon will be listed here.

Abstract

Importance: The family Herpesviridae consists of human and veterinary pathogens that cause a wide range of diseases in their respective hosts. These viruses share structurally related icosahedral capsids that encase the double-stranded DNA (dsDNA) viral genome. The dynamics of capsid assembly and maturation have been inaccessible to examination in living cells. This study has overcome this technical hurdle and provides new insights into this fundamental stage of herpesvirus infection.

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