Evaluation of the Characteristics of Hepatic Focal Nodular Hyperplasia: Correlation Between Dynamic Contrast-enhanced Multislice Computed Tomography and Pathological Findings

Overview

Journal Onco Targets Ther

Publisher Dove Medical Press

Specialty Oncology

Date 2016 Sep 1

PMID 27578988

Citations 2

Authors

Hai-Tao Zhang

Xin-Yi Gao

Qin-Sha Xu

Yu-Tang Chen

Yu-Piao Song

Zhen-Wei Yao

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the characteristics of enhancement of focal nodular hyperplasia (FNH) of the liver by analyzing the dynamic contrast-enhanced multislice computed tomography (MSCT) features and correlating them with pathological findings.

Patients And Methods: Nine males and 16 females with pathologically confirmed FNH and complete preoperative contrast-enhanced MSCT data were recruited for this study. The imaging features of FNH on the pre- and postcontrast MSCT were analyzed by two experienced radiologists by consensus.

Results: Pathology showed central scars and abnormal blood vessels in 17 and 21 of 25 lesions, respectively, while MSCT with multiphase enhancement showed central scars in eight of the 17 lesions (47.1%) and abnormal arteries or draining veins in 13 of the 21 lesions (61.9%). Furthermore, abnormal draining veins in five lesions were found to be diagnostic, which is another important finding.

Conclusion: Multiphase scanning can provide the panorama of FNH lesions and reveal their enhancement patterns and pathological characteristics. Abnormal blood vessels within or around the lesion are demonstrated more often than central scar, and both should be observed for FNH diagnosis.

Citing Articles

Correlation between magnetic resonance imaging (MRI) features and lesion size in focal nodular hyperplasia of the liver.

Pan Y, Liu W, Shan Y, Lin J, Xu P Quant Imaging Med Surg. 2024; 14(12):8758-8770.

PMID: 39698617 PMC: 11652048. DOI: 10.21037/qims-24-836.

Multi-parameter ultrasound based on the logistic regression model in the differential diagnosis of hepatocellular adenoma and focal nodular hyperplasia.

Wu M, Zhou R, Xu F, Li X, Zhao P, Yuan R World J Gastrointest Oncol. 2020; 11(12):1193-1205.

PMID: 31908724 PMC: 6937441. DOI: 10.4251/wjgo.v11.i12.1193.

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