Semen Proteomics and Male Infertility

Overview

Journal J Proteomics

Publisher Elsevier

Specialty Biochemistry

Date 2016 Aug 31

PMID 27576136

Citations 58

Authors

Meritxell Jodar

Ada Soler-Ventura

Rafael Oliva

Affiliations

Soon will be listed here.

Abstract

Significance: The review updates the numerous proteomics studies performed on semen, including spermatozoa and seminal fluid. In addition, an integrative analysis of the testes, sperm and seminal fluid proteomes is also included providing insights into the molecular mechanisms that regulate the generation, maturation and transit of spermatozoa. Furthermore, the compilation of several differential proteomic studies focused on male infertility reveals potential pathways disturbed in specific subtypes of male infertility and points out towards future research directions in the field.

Citing Articles

Proteomics and Metabolomics in Varicocele-Associated Male Infertility: Advancing Precision Diagnostics and Therapy.

Kaltsas A, Zikopoulos A, Markou E, Zachariou A, Stavropoulos M, Kratiras Z J Clin Med. 2024; 13(23).

PMID: 39685846 PMC: 11642067. DOI: 10.3390/jcm13237390.

Comparative Analysis of Fluorescence In Situ Hybridization and Next-Generation Sequencing in Sperm Evaluation: Implications for Preimplantation Genetic Testing and Male Infertility.

Moustakli E, Gkountis A, Dafopoulos S, Zikopoulos A, Sotiriou S, Zachariou A Int J Mol Sci. 2024; 25(20).

PMID: 39457078 PMC: 11508275. DOI: 10.3390/ijms252011296.

Assessing the Relationship between proAKAP4 Level and Longevity of Sexed Sperm Quality after Thawing.

Bastan I, Korkmaz F, Sahin D, Simsek S, Kaya U Vet Sci. 2024; 11(9).

PMID: 39330823 PMC: 11436178. DOI: 10.3390/vetsci11090444.

Intraindividual variability of semen quality, proteome, and sncRNA profiles in a healthy cohort of young adults.

Sergeyev O, Bezuglov V, Soloveva N, Smigulina L, Denisova T, Dikov Y Andrology. 2024; .

PMID: 39230333 PMC: 11876466. DOI: 10.1111/andr.13739.

Role of genetic variations and protein expression of β-Microsemino protein in intrauterine insemination outcome of unexplained infertile men: A case-control study.

Bagherian E, Jokari S, Boroujeni P, Haratian K, Sabbaghian M, Meybodi A Int J Reprod Biomed. 2024; 22(6):481-494.

PMID: 39205920 PMC: 11347762. DOI: 10.18502/ijrm.v22i6.16799.