[Bizarre Parosteal Osteochondromatous Proliferation of the Metatarsal Bone]
Overview
Affiliations
A bizarre parosteal osteochondromatous proliferation (BPOP), also known as a Nora lesion, is a rare benign bone formation. It emanates mainly from the intact cortex of the metaphysis of short tubular bones (hands or feet). Conventional radiographs should be complemented using cross-sectional imaging modalities (CT/MRI). In the absence of symptoms a non-operative regime with radiological and clinical controls is possible. If symptomatic, excision biopsy is the treatment of choice, though a high recurrence rate has been reported. Histopathological examination confirms the diagnosis and typically shows an endochondral ossification zone and an unusually mineralized cartilaginous matrix referred to as "blue bone".
First presentation of a Nora-lesion of the talus in a paraossal fasciitis.
Rottler P, Wilke A, Kasper H, Hutter F Orthop Rev (Pavia). 2019; 11(1):7628.
PMID: 30996837 PMC: 6452091. DOI: 10.4081/or.2019.7628.
Bizarre parosteal osteochondromatous proliferation of the femur: A case report.
Takahashi R, Matsuo T, Kawanami K, Takata T, Takahashi E, Deie M J Orthop. 2018; 15(2):606-609.
PMID: 29881204 PMC: 5990242. DOI: 10.1016/j.jor.2018.05.009.