Four New Dicaffeoylquinic Acid Derivatives from Glasswort (Salicornia Herbacea L.) and Their Antioxidative Activity

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2016 Aug 25

PMID 27556430

Citations 16

Authors

Jeong-Yong Cho

Jin Young Kim

Yu Geon Lee

Hyoung Jae Lee

Hyun Jeong Shim

Ji Hye Lee

Seon-Jae Kim

Kyung-Sik Ham

Jae-Hak Moon

Affiliations

Soon will be listed here.

Abstract

Four new dicaffeoylquinic acid derivatives and two known 3-caffeoylquinic acid derivatives were isolated from methanol extracts using the aerial parts of Salicornia herbacea. The four new dicaffeoylquinic acid derivatives were established as 3-caffeoyl-5-dihydrocaffeoylquinic acid, 3-caffeoyl-5-dihydrocaffeoylquinic acid methyl ester, 3-caffeoyl-4-dihydrocaffeoylquinic acid methyl ester, and 3,5-di-dihydrocaffeoylquinic acid methyl ester. Their chemical structures were determined by nuclear magnetic resonance and electrospray ionization-mass spectroscopy (LC-ESI-MS). In addition, the presence of dicaffeoylquinic acid derivatives in this plant was reconfirmed by LC-ESI-MS/MS analysis. The isolated compounds strongly scavenged 1,1-diphenyl-2-picrylhydrazyl radicals and inhibited cholesteryl ester hydroperoxide formation during rat blood plasma oxidation induced by copper ions. These results indicate that the caffeoylquinic acid derivatives may partially contribute to the antioxidative effect of S. herbacea.

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