Cognitive Function Assessment in Patients with End- Stage Renal Disease in Nigeria: A Single Center Experience

Overview

Journal Ann Afr Med

Specialty General Medicine

Date 2016 Aug 24

PMID 27549419

Citations 2

Authors

Lukman Femi Owolabi

Aliyu Abdu

Aliyu Ibrahim

Desola Shakira Owolabi

Aisha Nalado

Adamu Bappa

Aminu Abdullahi Taura

Affiliations

Soon will be listed here.

Abstract

Aim: The purpose of this comparative study was to evaluate cognitive function in end-stage renal disease (ESRD) patients in comparison with age, sex, and level of education-matched control.

Materials And Methods: This is a cross-sectional study involving 80 ESRD patients receiving maintenance hemodialysis treatment and recruited conservatively at the nephrology unit of our hospital. Eighty apparently healthy control, that were matched with the patients for age, sex and education, were also recruited. Following exclusion of depression and severe functional disability, a computer-assisted neuropsychological test, the FePsy, was used to assess memory, psychomotor speed, concentration and attention using simple auditory and visual reaction time tasks, recognition memory tests (RMTs), finger tapping task, and binary choice task (BCT) for both the ESRD patients and controls.

Results: ESRD patients performed worse on simple auditory and visual reaction time tasks (P < 0.05), RMTs (P < 0.05), finger tapping task (P < 0.05), BCT, and computerized visual search task (P < 0.05).

Conclusion: Performance in memory, psychomotor tasks, concentration, and attention tasks were found to be reduced among patients with ESRD compared with age, sex and level of education-matched control.

Citing Articles

Cognitive Dysfunction and Its Risk Factors in Patients Undergoing Maintenance Hemodialysis.

Tian X, Xia X, Yu H, Chen H, Jiang A, Xin L Neuropsychiatr Dis Treat. 2022; 18:2759-2769.

PMID: 36452115 PMC: 9704003. DOI: 10.2147/NDT.S380518.

A holistic approach to factors affecting depression in haemodialysis patients.

Gerogianni G, Kouzoupis A, Grapsa E Int Urol Nephrol. 2018; 50(8):1467-1476.

PMID: 29779116 DOI: 10.1007/s11255-018-1891-0.

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