Fetal Physiology and the Transition to Extrauterine Life

Overview

Journal Clin Perinatol

Date 2016 Aug 16

PMID 27524443

Citations 90

Authors

Sarah U Morton

Dara Brodsky

Affiliations

Soon will be listed here.

Abstract

The physiology of the fetus is fundamentally different from the neonate, with both structural and functional distinctions. The fetus is well-adapted to the relatively hypoxemic intrauterine environment. The transition from intrauterine to extrauterine life requires rapid, complex, and well-orchestrated steps to ensure neonatal survival. This article explains the intrauterine physiology that allows the fetus to survive and then reviews the physiologic changes that occur during the transition to extrauterine life. Asphyxia fundamentally alters the physiology of transition and necessitates a thoughtful approach in the management of affected neonates.

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