» Articles » PMID: 27522164

Circulating Tumor Cells in a Phase 3 Study of Docetaxel and Prednisone with or Without Lenalidomide in Metastatic Castration-resistant Prostate Cancer

Abstract

Patient Summary: Our study in metastatic castration-resistant prostate cancer patients treated with docetaxel chemotherapy, with or without lenalidomide, showed that patient survival was best predicted by circulating tumor cell count at the start of treatment. A rising circulating tumor cell count after three cycles of therapy predicted poor survival, while a decline predicted good survival.

Citing Articles

From microscopes to molecules: The evolution of prostate cancer diagnostics.

Tao J, Bian X, Zhou J, Zhang M Cytojournal. 2024; 21:29.

PMID: 39391208 PMC: 11464998. DOI: 10.25259/Cytojournal_36_2024.


Comparative efficacy of olaparib in combination with or without novel antiandrogens for treating metastatic castration-resistant prostate cancer.

Chen X, Pan Y, Wang Q, Ren C, Li M, Hao X Front Endocrinol (Lausanne). 2023; 14:1225033.

PMID: 38027160 PMC: 10644304. DOI: 10.3389/fendo.2023.1225033.


Prognostic Role of Circulating Tumor Cells in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Cabazitaxel: A Prospective Biomarker Study.

Koinis F, Zafeiriou Z, Messaritakis I, Katsaounis P, Koumarianou A, Kontopodis E Cancers (Basel). 2023; 15(18).

PMID: 37760481 PMC: 10527446. DOI: 10.3390/cancers15184511.


Utilization of Circulating Tumor Cells in the Management of Solid Tumors.

Kurniali P, Storandt M, Jin Z J Pers Med. 2023; 13(4).

PMID: 37109080 PMC: 10145886. DOI: 10.3390/jpm13040694.


Baseline CTC Count as a Predictor of Long-Term Outcomes in High-Risk Prostate Cancer.

Cieslikowski W, Milecki P, Swierczewska M, Ida A, Kasperczak M, Jankowiak A J Pers Med. 2023; 13(4).

PMID: 37108995 PMC: 10144132. DOI: 10.3390/jpm13040608.