A Versatile Axle for the Construction of Disassemblage Rotaxanes

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2016 Aug 13

PMID 27517897

Authors

Lucas A Powers

David B Smithrud

Affiliations

Soon will be listed here.

Abstract

Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and ¹H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors.

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