Recent Advances in Phototherapy for Psoriasis

Overview

Journal F1000Res

Specialties Biomedical Engineering
Science

Date 2016 Aug 9

PMID 27499849

Citations 5

Authors

Mio Nakamura

Benjamin Farahnik

Tina Bhutani

Affiliations

Soon will be listed here.

Abstract

Phototherapy involves repeated exposure of the skin to ultraviolet light to treat various inflammatory skin conditions such as psoriasis. Recent studies have identified specific immunologic effects of phototherapy that may underlie phototherapy efficacy. Furthermore, recent advancements have been made in developing safe and effective targeted phototherapy modalities for difficult-to-treat areas such as scalp psoriasis. Targeted phototherapy in the form of the excimer laser holds potential for more aggressive, effective treatment and long-lasting remission of psoriasis. Phototherapy is now also used successfully with biologic agents as combination therapy to treat recalcitrant psoriasis. Therefore, though one of the oldest therapeutic modalities for psoriasis, phototherapy remains a mainstay treatment with promise for further advancement.

Citing Articles

Lipid-based nanoparticles for psoriasis treatment: a review on conventional treatments, recent works, and future prospects.

Mohd Nordin U, Ahmad N, Salim N, Mohd Yusof N RSC Adv. 2022; 11(46):29080-29101.

PMID: 35478537 PMC: 9038133. DOI: 10.1039/d1ra06087b.

Phototherapy.

Barros N, Sbroglio L, Buffara M, Baka J, Pessoa A, Azulay-Abulafia L An Bras Dermatol. 2021; 96(4):397-407.

PMID: 33849754 PMC: 8245715. DOI: 10.1016/j.abd.2021.03.001.

Home Narrowband Ultraviolet B Phototherapy for Photoresponsive Skin Conditions: A Health Technology Assessment.

Ont Health Technol Assess Ser. 2020; 20(12):1-134.

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Unexpected dose response of HaCaT to UVB irradiation.

Chang R, Chen C, Huang C, Chang C, Cui Y, Chung W In Vitro Cell Dev Biol Anim. 2018; 54(8):589-599.

PMID: 30083841 DOI: 10.1007/s11626-018-0280-4.

T cell-intrinsic prostaglandin E-EP2/EP4 signaling is critical in pathogenic T17 cell-driven inflammation.

Lee J, Aoki T, Thumkeo D, Siriwach R, Yao C, Narumiya S J Allergy Clin Immunol. 2018; 143(2):631-643.

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