Contact Lens-induced Limbal Stem Cell Deficiency

Overview

Journal Ocul Surf

Specialty Ophthalmology

Date 2016 Aug 3

PMID 27480488

Citations 24

Authors

Jennifer Rossen

Alec Amram

Behrad Milani

Dongwook Park

Jennifer Harthan

Charlotte Joslin

Timothy McMahon

Ali Djalilian

Affiliations

Soon will be listed here.

Abstract

Limbal stem cell deficiency (LSCD) is a pathologic condition caused by the dysfunction and/or destruction of stem cell precursors of the corneal epithelium, typified clinically by corneal conjunctivalization. The purpose of this review is to critically discuss a less well-known cause of limbal stem cell disease: contact lens (CL) wear. A literature search was conducted to include original articles containing patients with CL-induced LSCD. This review describes epidemiology, diagnostic strategies, pathogenesis, differential diagnosis, and treatment modalities for this condition.

Citing Articles

Evaluation of Medically Reversible Limbal Stem Cell Deficiency.

Korkmaz I, Eratilgan N, Palamar M, Egrilmez S, Yagci A, Selver O Turk J Ophthalmol. 2024; 54(5):251-256.

PMID: 39463138 PMC: 11589240. DOI: 10.4274/tjo.galenos.2024.69705.

Corneal scarring after epithelium-off collagen cross-linking.

Natarajan R, Giridhar D Indian J Ophthalmol. 2024; 73(1):28-34.

PMID: 39297498 PMC: 11831937. DOI: 10.4103/IJO.IJO_95_24.

Prevalence of limbal stem cell deficiency at an academic referral center over a two-year period.

Goldberg J, Fraser D, Hou J Front Ophthalmol (Lausanne). 2024; 4:1392106.

PMID: 38984131 PMC: 11228361. DOI: 10.3389/fopht.2024.1392106.

A Review of Contact Lens-Induced Limbal Stem Cell Deficiency.

Lee Y, Yong D, Manotosh R Biology (Basel). 2023; 12(12).

PMID: 38132316 PMC: 10740976. DOI: 10.3390/biology12121490.

Strategic combination of cultivated oral mucosal epithelial transplantation and postoperative limbal-rigid contact lens-wear for end-stage ocular surface disease: a retrospective cohort study.

Aziza Y, Imai K, Itoi M, Yoshioka H, Komai S, Kitazawa K Br J Ophthalmol. 2023; 108(8):1177-1183.

PMID: 37918892 PMC: 11287622. DOI: 10.1136/bjo-2023-323617.

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