» Articles » PMID: 27478584

Metastatic Clear Cell Renal Cell Carcinoma Presenting with a Gingival Metastasis

Overview
Journal Clin Pract
Publisher MDPI
Specialty General Medicine
Date 2016 Aug 2
PMID 27478584
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

Metastatic deposits to the oral cavity are exceptionally rare. The commonest tumor types metastasizing to the oral cavity include lung and breast carcinoma. Renal cell carcinoma is believed to be the third most common infra clavicular tumor to metastasize to the head and neck. We report a case where an oral cavity deposit was the initial presentation for an occult clear cell renal carcinoma. Additional therapeutic options, including immunotherapy, tyrosine kinase inhibitors, and participation in a clinical trial, should be discussed with the patient despite the poor overall prognosis.

Citing Articles

Unpredictable Metastasis in the Head and Neck Region: A Diagnostic Immunohistochemical Challenge.

Closca R, Nicoara A, Rakitovan M, Mot I, Baderca F Diagnostics (Basel). 2023; 13(23).

PMID: 38066754 PMC: 10706832. DOI: 10.3390/diagnostics13233513.


Differential Diagnosis between Oral Metastasis of Renal Cell Carcinoma and Salivary Gland Cancer.

Morita Y, Kashima K, Suzuki M, Kinosada H, Teramoto A, Matsumiya Y Diagnostics (Basel). 2021; 11(3).

PMID: 33809250 PMC: 7999008. DOI: 10.3390/diagnostics11030506.


Metastatic disease in head & neck oncology.

Pisani P, Airoldi M, Allais A, Aluffi Valletti P, Battista M, Benazzo M Acta Otorhinolaryngol Ital. 2020; 40(SUPPL. 1):S1-S86.

PMID: 32469009 PMC: 7263073. DOI: 10.14639/0392-100X-suppl.1-40-2020.


Renal cell carcinoma metastatic to the maxillary gingiva: A case report and review of the literature.

Vasilyeva D, Peters S, Philipone E, Yoon A J Oral Maxillofac Pathol. 2018; 22(Suppl 1):S102-S107.

PMID: 29491617 PMC: 5824500. DOI: 10.4103/jomfp.JOMFP_69_17.


Epulis-Like Presentation of Gingival Renal Cancer Metastasis.

Nifosi G, Bressand H, Nifosi A, Nifosi L, Damseaux P Case Rep Oncol. 2017; 10(2):758-763.

PMID: 28878662 PMC: 5582523. DOI: 10.1159/000479500.


References
1.
Mai K, Landry D, Robertson S, Commons A, Burns B, Thijssen A . A comparative study of metastatic renal cell carcinoma with correlation to subtype and primary tumor. Pathol Res Pract. 2001; 197(10):671-5. DOI: 10.1078/0344-0338-00144. View

2.
Hirshberg A, Leibovich P, Buchner A . Metastases to the oral mucosa: analysis of 157 cases. J Oral Pathol Med. 1993; 22(9):385-90. DOI: 10.1111/j.1600-0714.1993.tb00128.x. View

3.
Nishimura Y, Yakata H, Kawasaki T, Nakajima T . Metastatic tumours of the mouth and jaws. A review of the Japanese literature. J Maxillofac Surg. 1982; 10(4):253-8. DOI: 10.1016/s0301-0503(82)80050-7. View

4.
ELLIS G, Jensen J, REINGOLD I, Barr R . Malignant neoplasms metastatic to gingivae. Oral Surg Oral Med Oral Pathol. 1977; 44(2):238-45. DOI: 10.1016/0030-4220(77)90274-2. View

5.
Azam F, Abubakerr M, Gollins S . Tongue metastasis as an initial presentation of renal cell carcinoma: a case report and literature review. J Med Case Rep. 2008; 2:249. PMC: 2495001. DOI: 10.1186/1752-1947-2-249. View