Tissue-specific and Hormonal Regulation of the Gene for Rat Prostatic Steroid-binding Protein in Transgenic Mice

Overview

Journal Mol Cell Biol

Specialty Cell Biology

Date 1989 May 1

PMID 2747651

Citations 8

Authors

J Allison

Y L Zhang

M G Parker

Affiliations

Soon will be listed here.

Abstract

We investigated the tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein by introducing the C3(1) gene with 4-kilobase (kb) upstream and 2-kb downstream flanking sequences into transgenic mice. There was selective expression in the ventral prostate that was stimulated by testosterone, which indicated that the gene together with 6-kb flanking DNA contains the information required for prostate-specific and testosterone-regulated expression.

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