Emergence of Mycoplasma Genitalium Strains Showing Mutations Associated with Macrolide and Fluoroquinolone Resistance in the Region Dresden, Germany

Overview

Journal Diagn Microbiol Infect Dis

Specialties Infectious Diseases
Microbiology
Pathology

Date 2016 Jul 25

PMID 27448452

Citations 23

Authors

Roger Dumke

Alexander Thurmer

Enno Jacobs

Affiliations

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Abstract

Among 323 specimens from male patients with symptoms of non-gonococcal urethritis, Mycoplasma genitalium was detected in 19 samples by real-time PCR. Mutations of 23S rRNA gene associated with macrolide resistance were confirmed in 10 strains. Amino acid changes at positions 81 and 83 of ParC protein were demonstrated indicating quinolone resistance of two strains.

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