Genetic, Hormonal and Metabolic Aspects of PCOS: an Update

Overview

Journal Reprod Biol Endocrinol

Publisher Biomed Central

Specialties Endocrinology
Reproductive Medicine

Date 2016 Jul 18

PMID 27423183

Citations 154

Authors

V De Leo

M C Musacchio

V Cappelli

M G Massaro

G Morgante

F Petraglia

Affiliations

Soon will be listed here.

Abstract

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5-10 % of women of reproductive age. It generally manifests with oligo/anovulatory cycles, hirsutism and polycystic ovaries, together with a considerable prevalence of insulin resistance. Although the aetiology of the syndrome is not completely understood yet, PCOS is considered a multifactorial disorder with various genetic, endocrine and environmental abnormalities. Moreover, PCOS patients have a higher risk of metabolic and cardiovascular diseases and their related morbidity, if compared to the general population.

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