Treatment of Paecilomyces Variotii Pneumonia with Posaconazole: Case Report and Literature Review

Overview

Journal Mycoses

Specialty Microbiology

Date 2016 Jul 13

PMID 27401982

Citations 15

Authors

Ryan Feldman

Leslie Cockerham

Blake W Buchan

Zouyan Lu

Angela M Huang

Affiliations

Soon will be listed here.

Abstract

The fungi Paecilomyces variotii is a potential pathogen in immunocompromised and immunocompetent patients. Their rare association with clinical disease results in scarce literature regarding susceptibility and treatment. Here, we discuss a case involving successful treatment of probable P. variotii pneumonia with posaconazole after treatment failure with voriconazole. The current literature related to antifungal susceptibility profiles, microbiological identification methods and clinical management of infections caused by this organism is also reviewed.

Citing Articles

Severe pneumonia with pleural effusion caused by co-infection of Paecilomyces variotii and Penicillium oxalicum in a diabetic patient.

Wang X, Chen X, Liang Y, Hu L BMC Infect Dis. 2024; 24(1):605.

PMID: 38898444 PMC: 11186164. DOI: 10.1186/s12879-024-09496-6.

Hypersensitivity pneumonitis with as suspected inciting antigen.

Watanabe M, Okuda R, Ishida Y, Sagawa S, Muraoka T, Ikeda S Respir Med Case Rep. 2024; 49:102013.

PMID: 38559328 PMC: 10975500. DOI: 10.1016/j.rmcr.2024.102013.

Successful Treatment of Pneumonia and Lupus Nephritis With Posaconazole-Cyclophosphamide Co-administration Without Drug Interaction-Induced Toxicity.

Pechacek J, Webb T, Ferre E, Schmitt M, DiMaggio T, Kobrin D Open Forum Infect Dis. 2023; 10(8):ofad410.

PMID: 37564740 PMC: 10411043. DOI: 10.1093/ofid/ofad410.

Non- Hyaline Molds: A Host-Based Perspective of Emerging Pathogenic Fungi Causing Sinopulmonary Diseases.

Jacobs S, Walsh T J Fungi (Basel). 2023; 9(2).

PMID: 36836326 PMC: 9964096. DOI: 10.3390/jof9020212.

Molecular epidemiology of clinical filamentous fungi in Qatar beyond Aspergillus and Fusarium with notes on the rare species.

Salah H, Houbraken J, Boekhout T, Almaslamani M, Taj-Aldeen S Med Mycol. 2023; 61(1).

PMID: 36592959 PMC: 9874029. DOI: 10.1093/mmy/myac098.