The Canadian Biliary Atresia Registry: Improving the Care of Canadian Infants with Biliary Atresia

Overview

Journal Paediatr Child Health

Publisher Oxford University Press

Specialty Pediatrics

Date 2016 Jul 12

PMID 27398049

Citations 4

Authors

Alison E Butler

Richard A Schreiber

Natalie Yanchar

Sherif Emil

Jean-Martin Laberge

Affiliations

Soon will be listed here.

Abstract

Biliary atresia is the most common cause of end-stage liver disease and liver cirrhosis in children, and the leading indication for liver transplantation in the paediatric population. There is no cure for biliary atresia; however, timely diagnosis and early infant age at surgical intervention using the Kasai portoenterostomy optimize the prognosis. Late referral is a significant problem in Canada and elsewhere. There is also a lack of standardized care practices among treating centres in this country. Biliary atresia registries currently exist across Europe, Asia and the United States. They have provided important evidence-based information to initiate changes to biliary atresia care in their countries with improvements in outcome. The Canadian Biliary Atresia Registry was initiated in 2013 for the purpose of identifying best standards of care, enhancing public education, facilitating knowledge translation and advocating for novel national public health policy programs to improve the outcomes of Canadian infants with biliary atresia.

Citing Articles

Primary antibiotic prophylaxis in biliary atresia did not demonstrate decreased infection rate: Multi-centre retrospective study.

Brody Y, Slae M, Amir A, Mozer-Glassberg Y, Bar-Lev M, Shteyer E Acta Paediatr. 2024; 114(3):654-659.

PMID: 39528247 PMC: 11828718. DOI: 10.1111/apa.17493.

Prognostic Factors Related to In-hospital Death in Children with Biliary Atresia: Analysis of a Nationwide Inpatient Database.

Shi Y, Jiang Y, Zhou G, Shi Y, Gan L, Kong Y J Clin Transl Hepatol. 2023; 11(2):416-424.

PMID: 36643040 PMC: 9817058. DOI: 10.14218/JCTH.2021.00456.

The Canadian Consortium for Research in Pediatric Surgery: Roadmap for Creation and Implementation of a National Subspecialty Research Consortium.

Emil S, Guadagno E, Baird R, Puligandla P, Romao R, Van HouWelingen L J Am Coll Surg. 2022; 235(6):952-961.

PMID: 36102499 PMC: 9653101. DOI: 10.1097/XCS.0000000000000396.

Portal plate bile duct diameter in biliary atresia is associated with long-term outcome.

Shpoliansky M, Tobar A, Mozer-Glassberg Y, Bar-Lev M, Shamir R, Shafir M Pediatr Surg Int. 2022; 38(6):825-831.

PMID: 35322291 DOI: 10.1007/s00383-022-05113-2.

Biliary Atresia - Too Few, Too Many Centers.

Amil Dias J GE Port J Gastroenterol. 2018; 25(2):57-58.

PMID: 29662927 PMC: 5892320. DOI: 10.1159/000484352.

References

Shneider B, Brown M, Haber B, Whitington P, Schwarz K, Squires R . A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000. J Pediatr. 2006; 148(4):467-474. DOI: 10.1016/j.jpeds.2005.12.054. View

Lin Y, Chang M, Liao S, Wu J, Ni Y, Tiao M . Decreasing rate of biliary atresia in Taiwan: a survey, 2004-2009. Pediatrics. 2011; 128(3):e530-6. DOI: 10.1542/peds.2011-0742. View

Schreiber R, Masucci L, Kaczorowski J, Collet J, Lutley P, Espinosa V . Home-based screening for biliary atresia using infant stool colour cards: a large-scale prospective cohort study and cost-effectiveness analysis. J Med Screen. 2014; 21(3):126-32. DOI: 10.1177/0969141314542115. View

Schreiber R, Barker C, Roberts E, Martin S . Biliary atresia in Canada: the effect of centre caseload experience on outcome. J Pediatr Gastroenterol Nutr. 2010; 51(1):61-5. DOI: 10.1097/MPG.0b013e3181d67e5e. View

Jones S, James E, Prasad S . Disease registries and outcomes research in children: focus on lysosomal storage disorders. Paediatr Drugs. 2010; 13(1):33-47. DOI: 10.2165/11586860-000000000-00000. View

Hartley J, Davenport M, Kelly D . Biliary atresia. Lancet. 2009; 374(9702):1704-13. DOI: 10.1016/S0140-6736(09)60946-6. View

Lampela H, Ritvanen A, Kosola S, Koivusalo A, Rintala R, Jalanko H . National centralization of biliary atresia care to an assigned multidisciplinary team provides high-quality outcomes. Scand J Gastroenterol. 2011; 47(1):99-107. DOI: 10.3109/00365521.2011.627446. View

Nio M, Ohi R, Miyano T, Saeki M, Shiraki K, Tanaka K . Five- and 10-year survival rates after surgery for biliary atresia: a report from the Japanese Biliary Atresia Registry. J Pediatr Surg. 2003; 38(7):997-1000. DOI: 10.1016/s0022-3468(03)00178-7. View

de Vries W, de Langen Z, Groen H, Scheenstra R, Peeters P, Hulscher J . Biliary atresia in the Netherlands: outcome of patients diagnosed between 1987 and 2008. J Pediatr. 2011; 160(4):638-644.e2. DOI: 10.1016/j.jpeds.2011.09.061. View

10.

Davenport M, Ong E, Sharif K, Alizai N, McClean P, Hadzic N . Biliary atresia in England and Wales: results of centralization and new benchmark. J Pediatr Surg. 2011; 46(9):1689-94. DOI: 10.1016/j.jpedsurg.2011.04.013. View

11.

Wildhaber B, Majno P, Mayr J, Zachariou Z, Hohlfeld J, Schwoebel M . Biliary atresia: Swiss national study, 1994-2004. J Pediatr Gastroenterol Nutr. 2008; 46(3):299-307. DOI: 10.1097/MPG.0b013e3181633562. View

12.

Lien T, Chang M, Wu J, Chen H, Lee H, Chen A . Effects of the infant stool color card screening program on 5-year outcome of biliary atresia in Taiwan. Hepatology. 2010; 53(1):202-8. DOI: 10.1002/hep.24023. View

13.

Schreiber R, Barker C, Roberts E, Martin S, Alvarez F, Smith L . Biliary atresia: the Canadian experience. J Pediatr. 2007; 151(6):659-65, 665.e1. DOI: 10.1016/j.jpeds.2007.05.051. View

14.

Sokol R . New North American research network focuses on biliary atresia and neonatal liver disease. J Pediatr Gastroenterol Nutr. 2003; 36(1):1. DOI: 10.1097/00005176-200301000-00001. View

15.

Chitsaz E, Schreiber R, Collet J, Kaczorowski J . Biliary atresia: the timing needs a changin'. Can J Public Health. 2010; 100(6):475-7. PMC: 6973595. View

16.

Petersen C, Harder D, Abola Z, Alberti D, Becker T, Chardot C . European biliary atresia registries: summary of a symposium. Eur J Pediatr Surg. 2008; 18(2):111-6. DOI: 10.1055/s-2008-1038479. View

17.

Zani A, Quaglia A, Hadzic N, Zuckerman M, Davenport M . Cytomegalovirus-associated biliary atresia: An aetiological and prognostic subgroup. J Pediatr Surg. 2015; 50(10):1739-45. DOI: 10.1016/j.jpedsurg.2015.03.001. View

18.

Chardot C, Buet C, Serinet M, Golmard J, Lachaux A, Roquelaure B . Improving outcomes of biliary atresia: French national series 1986-2009. J Hepatol. 2013; 58(6):1209-17. DOI: 10.1016/j.jhep.2013.01.040. View