Effect of Aerobic Exercise and Raloxifene Combination Therapy on Senile Osteoporosis

Overview

Journal J Phys Ther Sci

Date 2016 Jul 9

PMID 27390417

Citations 4

Authors

Chengjin Zhao

Haibing Hou

Yutao Chen

Kai Lv

Affiliations

Soon will be listed here.

Abstract

[Purpose] This study assessed the effects of combined application of raloxifene and aerobic exercise on senile osteoporosis. [Subjects and Methods] A total of 70 elderly patients with osteoporosis, who treated at our hospital between April 2013 and August 2014, were divided into equal-sized observation and control groups. The control group was administered raloxifene, whereas the observation group received raloxifene treatment plus aerobic exercise. [Results] Outpatient outcomes were considered dependent variables. After treatment, the two groups differed significantly in terms of lumbar spine (L2-L4) and proximal femoral bone mineral density. The urine pyridine/creatinine ratio decreased significantly and serum calcitonin level increased significantly in the observation group. These differences were statistically significant. [Conclusion] Raloxifene combined with aerobic exercise therapy significantly improves bone density and promotes bone formation in patients with senile osteoporosis.

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