All in One: Researchers Create Combination Drugs for Diabetes and Obesity
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Molecular Biology
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Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake.
Ouberai M, Gomes Dos Santos A, Kinna S, Hornigold D, Baker D, Naylor J Front Endocrinol (Lausanne). 2023; 14:1217021.
PMID: 37554763 PMC: 10406450. DOI: 10.3389/fendo.2023.1217021.
Prediction of drug combination effects with a minimal set of experiments.
Ianevski A, Giri A, Gautam P, Kononov A, Potdar S, Saarela J Nat Mach Intell. 2020; 1(12):568-577.
PMID: 32368721 PMC: 7198051. DOI: 10.1038/s42256-019-0122-4.
Battle of GLP-1 delivery technologies.
Yu M, Benjamin M, Srinivasan S, Morin E, Shishatskaya E, Schwendeman S Adv Drug Deliv Rev. 2018; 130:113-130.
PMID: 30009885 PMC: 6843995. DOI: 10.1016/j.addr.2018.07.009.
Ghrelin regulation of glucose metabolism.
Poher A, Tschop M, Muller T Peptides. 2018; 100:236-242.
PMID: 29412824 PMC: 5805851. DOI: 10.1016/j.peptides.2017.12.015.
Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly.
Ouberai M, Gomes Dos Santos A, Kinna S, Madalli S, Hornigold D, Baker D Nat Commun. 2017; 8(1):1026.
PMID: 29044101 PMC: 5647335. DOI: 10.1038/s41467-017-01114-1.