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Interventional Pain Management Approaches for Control of Chronic Pancreatic Pain

Overview
Specialty Gastroenterology
Date 2016 Jul 2
PMID 27363978
Citations 2
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Abstract

Treatment of persistent pain from chronic pancreatitis historically was difficult to treat. For years, focus was on opioid and other analgesics and psychological treatments. Recent studies provided evidence for decrease in analgesic intake and pain scores after properly conducted sympathetic blocks (celiac, splanchnic nerve blocks). These therapies should be considered as parts of a multimodal analgesic strategy. Animal studies suggest that spinal cord stimulation suppresses visceral hyperalgesia. Large case series of spinal cord stimulation demonstrated a significant pain relief in patients with chronic pancreatitis. Given the limitations of conservative and surgical treatments for chronic visceral pain, spinal cord stimulation may be a very useful therapeutic option.

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Endoscopic Ultrasound-Guided Management of Pain in Chronic Pancreatitis and Pancreatic Cancer: an Update.

Wyse J, Sahai A Curr Treat Options Gastroenterol. 2018; 16(4):417-427.

PMID: 30209676 DOI: 10.1007/s11938-018-0193-z.


Opioid misuse in gastroenterology and non-opioid management of abdominal pain.

Szigethy E, Knisely M, Drossman D Nat Rev Gastroenterol Hepatol. 2017; 15(3):168-180.

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