Gallium and Functionalized-Porphyrins Combine to Form Potential Lysosome-Specific Multimodal Bioprobes

Overview

Journal Inorg Chem

Specialty Chemistry

Date 2016 Jun 30

PMID 27355871

Citations 2

Authors

Jie Pan

Bethany I Harriss

Chi-Fai Chan

Lijun Jiang

Tik-Hung Tsoi

Nicholas J Long

Wing-Tak Wong

Wai-Kwok Wong

Ka-Leung Wong

Affiliations

Soon will be listed here.

Abstract

A water-soluble bimetallic normal ("cold") and radiochemical ("hot") gallium-porphyrin-ruthenium-bipyridine complex (GaporRu-1) has been synthesized by microwave methodology in short reaction times with good (>85%) yields. (68)GaporRu-1 is demonstrated to be a potential multimodal and functional bioprobe for positron emission tomography (PET), lysosome specific optical imaging, and photodynamic therapy.

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