Marburg Virus Reverse Genetics Systems

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2016 Jun 25

PMID 27338448

Citations 11

Authors

Kristina Maria Schmidt

Elke Muhlberger

Affiliations

Soon will be listed here.

Abstract

The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses. Reverse genetics systems established for MARV have been used to study various aspects of the viral replication cycle, analyze host responses, image viral infection, and screen for antivirals. This article provides an overview of the currently established MARV reverse genetic systems based on minigenomes, infectious virus-like particles and full-length clones, and the research that has been conducted using these systems.

Citing Articles

A comparative analysis of Marburg virus-infected bat and human models from public high-throughput sequencing data.

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Transcription- and Replication-Competent Virus-like Particle Systems for Marburg Virus.

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Developments in Negative-Strand RNA Virus Reverse Genetics.

Wang M, Wu J, Cao X, Xu L, Wu J, Ding H Microorganisms. 2024; 12(3).

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Recent insights into reverse genetics of norovirus.

Zhang Q, Zhu S, Zhang X, Su L, Ni J, Zhang Y Virus Res. 2023; 325:199046.

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