» Articles » PMID: 27325067

Effects of Environmental Exposures on Fetal and Childhood Growth Trajectories

Abstract

Delayed fetal growth and adverse birth outcomes are some of the greatest public health threats to this generation of children worldwide because these conditions are major determinants of mortality, morbidity, and disability in infancy and childhood and are also associated with diseases in adult life. A number of studies have investigated the impacts of a range of environmental conditions during pregnancy (including air pollution, endocrine disruptors, persistent organic pollutants, heavy metals) on fetal and child development. The results, while provocative, have been largely inconsistent. This review summarizes up to date epidemiologic studies linking major environmental pollutants to fetal and child development and suggested future directions for further investigation.

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References
1.
Vigeh M, Yokoyama K, Ramezanzadeh F, Dahaghin M, Sakai T, Morita Y . Lead and other trace metals in preeclampsia: a case-control study in Tehran, Iran. Environ Res. 2005; 100(2):268-75. DOI: 10.1016/j.envres.2005.05.005. View

2.
Forsen T, Eriksson J, Tuomilehto J, Reunanen A, Osmond C, Barker D . The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med. 2000; 133(3):176-82. DOI: 10.7326/0003-4819-133-3-200008010-00008. View

3.
Wasowicz W, Wolkanin P, Bednarski M, Gromadzinska J, Sklodowska M, Grzybowska K . Plasma trace element (Se, Zn, Cu) concentrations in maternal and umbilical cord blood in Poland. Relation with birth weight, gestational age, and parity. Biol Trace Elem Res. 1993; 38(2):205-15. DOI: 10.1007/BF02784053. View

4.
Mahomed K, Bhutta Z, Middleton P . Zinc supplementation for improving pregnancy and infant outcome. Cochrane Database Syst Rev. 2007; (2):CD000230. DOI: 10.1002/14651858.CD000230.pub3. View

5.
Rich D, Demissie K, Lu S, Kamat L, Wartenberg D, Rhoads G . Ambient air pollutant concentrations during pregnancy and the risk of fetal growth restriction. J Epidemiol Community Health. 2009; 63(6):488-96. PMC: 4019072. DOI: 10.1136/jech.2008.082792. View