» Articles » PMID: 27303141

Acute Fibrinous and Organizing Pneumonia: A Rare Form of Nonbacterial Pneumonia

Overview
Specialty Critical Care
Date 2016 Jun 16
PMID 27303141
Citations 7
Authors
Affiliations
Soon will be listed here.
Abstract

Acute fibrinous and organizing pneumonia (AFOP) is a rare disease characterized by bilateral basilar infiltrates and histological findings of organizing pneumonia and intra-alveolar fibrin in the form of "fibrin balls." Here, we report a 43-year-old female with complaints of fever, dry cough, and shortness of breath with hypoxemia. High-resolution computed tomography thorax revealed diffuse confluent consolidation in bilateral lung zones. Bronchoscopy and transbronchial biopsy revealed features of AFOP. With prednisolone treatment, there was an improvement in her condition. AFOP is a rare disease and should be taken into consideration and differential diagnosis of severe acute pneumonias with no significant comorbidities.

Citing Articles

Acute fibrinous and organizing pneumonia associated with Candida: A case report.

Li Z, Xu B, Liu J Respir Med Case Rep. 2024; 52:102120.

PMID: 39429648 PMC: 11490896. DOI: 10.1016/j.rmcr.2024.102120.


Acute lung injury-from cannabis to COVID.

Beasley M Mod Pathol. 2021; 35(Suppl 1):1-7.

PMID: 34504310 PMC: 8428494. DOI: 10.1038/s41379-021-00915-6.


Diagnostic procedures and clinico-radiological findings of acute fibrinous and organizing pneumonia: a systematic review and pooled analysis.

Lee J, Yum H, Jamous F, Santos C, Campisi A, Surani S Eur Radiol. 2021; 31(10):7283-7294.

PMID: 33791819 DOI: 10.1007/s00330-021-07868-z.


Pathophysiology of acute fibrinous and organizing pneumonia - Clinical and morphological spectra.

Santos C, Oliveira R, Serra P, Baptista J, Sousa E, Casanova P Pathophysiology. 2019; 26(3-4):213-217.

PMID: 31076239 PMC: 7126839. DOI: 10.1016/j.pathophys.2019.04.001.


Acute fibrinous and organizing pneumonia: A case report.

Wang Y, Li Y, Wang Q, Zhang L, Li J, Zhu C Medicine (Baltimore). 2019; 98(8):e14537.

PMID: 30813161 PMC: 6408101. DOI: 10.1097/MD.0000000000014537.


References
1.
Valim V, Rocha R, Couto R, Paixao T, Serrano E . Acute fibrinous and organizing pneumonia and undifferentiated connective tissue disease: a case report. Case Rep Rheumatol. 2012; 2012:549298. PMC: 3420729. DOI: 10.1155/2012/549298. View

2.
Sauter J, Butnor K . Expanding the spectrum of pulmonary histopathological manifestations of anti-synthetase syndrome: anti-EJ-associated acute fibrinous and organizing pneumonia. Histopathology. 2014; 65(4):581-2. DOI: 10.1111/his.12420. View

3.
Bhatti S, Hakeem A, Torrealba J, McMahon J, Meyer K . Severe acute fibrinous and organizing pneumonia (AFOP) causing ventilatory failure: successful treatment with mycophenolate mofetil and corticosteroids. Respir Med. 2009; 103(11):1764-7. DOI: 10.1016/j.rmed.2009.07.009. View

4.
Voloudaki A, Bouros D, Froudarakis M, Datseris G, Apostolaki E, Gourtsoyiannis N . Crescentic and ring-shaped opacities. CT features in two cases of bronchiolitis obliterans organizing pneumonia (BOOP). Acta Radiol. 1996; 37(6):889-92. DOI: 10.1177/02841851960373P289. View

5.
Kuza C, Matheos T, Kathman D, Heard S . Life after acute fibrinous and organizing pneumonia: a case report of a patient 30 months after diagnosis and review of the literature. J Crit Care. 2015; 31(1):255-61. PMC: 7126573. DOI: 10.1016/j.jcrc.2015.10.002. View