Richter's Transformation Presenting As Splenic Rupture After 6 Years of Complete Remission of Chronic Lymphocytic Leukaemia

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2016 Jun 12

PMID 27288204

Citations 1

Authors

Braghadheeswar Thyagarajan

Sayee Sundar Alagusundaramoorthy

Lopa Shah

Abhinav Agrawal

Affiliations

Soon will be listed here.

Abstract

Richter's transformation is a rare clinical condition occurring in about 5-10% of patients with chronic lymphocytic leukaemia (CLL). Patients usually present with lymphadenopathy, hepatosplenomegaly and elevated serum lactate dehydrogenase levels. These patients have a very poor prognosis with a median survival of about 10 months. We present a patient, with a history of CLL in complete remission, who presented with splenic rupture requiring splenectomy. She was eventually diagnosed with diffuse large B-cell lymphoma with Richter's transformation.

Citing Articles

Unique case of atraumatic splenic rupture in a patient with chronic lymphocytic leukaemia with Richter's transformation.

Paduri S, Nandu N, Brucker T, Roach P, Pant-Purohit M BMJ Case Rep. 2021; 14(10).

PMID: 34670746 PMC: 8529982. DOI: 10.1136/bcr-2021-242193.

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