The PLE(2)NO Self-management and Exercise Program for Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial

Overview

Journal BMC Musculoskelet Disord

Publisher Biomed Central

Specialties Orthopedics
Physiology

Date 2016 Jun 9

PMID 27267755

Citations 3

Authors

Priscila Marconcin

Margarida Espanha

Flavia Yazigi

Pedro Campos

Affiliations

Soon will be listed here.

Abstract

Background: International recommendations suggest exercise and self-management programs, including non-pharmacological treatments, for knee osteoarthritis (KOA) because they can benefit pain relief and improve function and exercise adherence. The implementation of a combined self-management and exercise program termed PLE(2)NO may be a good method for controlling KOA symptoms because it encourages the development of self-efficacy to manage the pathology. This study will assess the effects of a self-management and exercise program in comparison to an educational intervention (control program) on symptoms, physical fitness, health-related quality of life, self-management behaviors, self-efficacy, physical activity level and coping strategies.

Methods/design: This PLE(2)NO study is a single-blinded, randomized controlled trial of elderly (aged above 60 yrs old) patients with clinical and radiographic KOA. The patients will be allocated into either an educational group (control) or a self-management and exercise group (experimental). All participants will receive a supplement of chondroitin and glucosamine sulfates. This paper describes the protocol that will be used in the PLE(2)NO program.

Discussion: This program has several strengths. First, it involves a combination of self-management and exercise approaches, is available in close proximity to the patients and occurs over a short period of time. The latter two characteristics are crucial for maintaining participant adherence. Exercise components will be implemented using low-cost resources that permit their widespread application. Moreover, the program will provide guidance regarding the effectiveness of using a self-management and exercise program to control KOA symptoms and improve self-efficacy and health-related quality of life.

Trial Registration: NCT02562833 (09/23/2015).

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The Influence of Physical Exercises on the Flexibility of Older Individuals with Knee Osteoarthritis: A Systematic Review.

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References

Lorig K, Sobel D, Stewart A, BROWN Jr B, Bandura A, Ritter P . Evidence suggesting that a chronic disease self-management program can improve health status while reducing hospitalization: a randomized trial. Med Care. 1999; 37(1):5-14. DOI: 10.1097/00005650-199901000-00003. View

Giampaoli S, Ferrucci L, Cecchi F, Lo Noce C, Poce A, Dima F . Hand-grip strength predicts incident disability in non-disabled older men. Age Ageing. 1999; 28(3):283-8. DOI: 10.1093/ageing/28.3.283. View

Maurer B, Stern A, Kinossian B, Cook K, Schumacher Jr H . Osteoarthritis of the knee: isokinetic quadriceps exercise versus an educational intervention. Arch Phys Med Rehabil. 1999; 80(10):1293-9. DOI: 10.1016/s0003-9993(99)90032-1. View

Barlow J, Turner A, Wright C . A randomized controlled study of the Arthritis Self-Management Programme in the UK. Health Educ Res. 2001; 15(6):665-80. DOI: 10.1093/her/15.6.665. View

Peat G, McCarney R, Croft P . Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis. 2001; 60(2):91-7. PMC: 1753462. DOI: 10.1136/ard.60.2.91. View

Sangha O . Epidemiology of rheumatic diseases. Rheumatology (Oxford). 2001; 39 Suppl 2:3-12. DOI: 10.1093/rheumatology/39.suppl_2.3. View

Penninx B, Messier S, Rejeski W, Williamson J, DiBari M, Cavazzini C . Physical exercise and the prevention of disability in activities of daily living in older persons with osteoarthritis. Arch Intern Med. 2001; 161(19):2309-16. DOI: 10.1001/archinte.161.19.2309. View

van Baar M, Dekker J, Oostendorp R, Bijl D, Voorn T, Bijlsma J . Effectiveness of exercise in patients with osteoarthritis of hip or knee: nine months' follow up. Ann Rheum Dis. 2001; 60(12):1123-30. PMC: 1753453. DOI: 10.1136/ard.60.12.1123. View

Lorig K, Sobel D, Ritter P, Laurent D, Hobbs M . Effect of a self-management program on patients with chronic disease. Eff Clin Pract. 2002; 4(6):256-62. View

10.

Tattersall R . The expert patient: a new approach to chronic disease management for the twenty-first century. Clin Med (Lond). 2002; 2(3):227-9. PMC: 4954037. DOI: 10.7861/clinmedicine.2-3-227. View

11.

Topp R, Woolley S, Hornyak 3rd J, Khuder S, Kahaleh B . The effect of dynamic versus isometric resistance training on pain and functioning among adults with osteoarthritis of the knee. Arch Phys Med Rehabil. 2002; 83(9):1187-95. DOI: 10.1053/apmr.2002.33988. View

12.

Boutaugh M . Arthritis Foundation community-based physical activity programs: effectiveness and implementation issues. Arthritis Rheum. 2003; 49(3):463-70. DOI: 10.1002/art.11050. View

13.

Huang M, Lin Y, Yang R, Lee C . A comparison of various therapeutic exercises on the functional status of patients with knee osteoarthritis. Semin Arthritis Rheum. 2003; 32(6):398-406. DOI: 10.1053/sarh.2003.50021. View

14.

Lorig K, Holman H . Self-management education: history, definition, outcomes, and mechanisms. Ann Behav Med. 2003; 26(1):1-7. DOI: 10.1207/S15324796ABM2601_01. View

15.

Craig C, Marshall A, Sjostrom M, Bauman A, Booth M, Ainsworth B . International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003; 35(8):1381-95. DOI: 10.1249/01.MSS.0000078924.61453.FB. View

16.

Kellgren J, Lawrence J . Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957; 16(4):494-502. PMC: 1006995. DOI: 10.1136/ard.16.4.494. View

17.

Roos E, Lohmander L . The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis. Health Qual Life Outcomes. 2003; 1:64. PMC: 280702. DOI: 10.1186/1477-7525-1-64. View

18.

Hurst H, Bolton J . Assessing the clinical significance of change scores recorded on subjective outcome measures. J Manipulative Physiol Ther. 2004; 27(1):26-35. DOI: 10.1016/j.jmpt.2003.11.003. View

19.

Hughes S, Seymour R, Campbell R, Pollak N, Huber G, Sharma L . Impact of the fit and strong intervention on older adults with osteoarthritis. Gerontologist. 2004; 44(2):217-28. DOI: 10.1093/geront/44.2.217. View

20.

Messier S, Loeser R, Miller G, Morgan T, Rejeski W, Sevick M . Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum. 2004; 50(5):1501-10. DOI: 10.1002/art.20256. View