Exopisiod B and Farylhydrazone C, Two New Alkaloids from the Antarctic-derived Fungus Penicillium Sp. HDN14-431

Overview

Journal J Asian Nat Prod Res

Publisher Informa Healthcare

Specialties Biology
Chemistry

Date 2016 Jun 2

PMID 27249624

Citations 4

Authors

Ting Zhang

Mei-Lin Zhu

Guang-Yu Sun

Na Li

Qian-Qun Gu

De-Hai Li

Qian Che

Tian-Jiao Zhu

Affiliations

Soon will be listed here.

Abstract

Two new compounds, exopisiod B (1) and farylhydrazone C (2), together with two known compounds (3-4), were isolated from the Antarctic-derived fungus Penicillium sp. HDN14-431. Their structures including absolute configurations were elucidated by spectroscopic methods and TDDFT ECD calculations. The cytotoxicity and antimicrobial activities of all compounds were tested.

Citing Articles

Metabolites isolated from HDS-Z-1E, an endophytic fungal strain isolated from and their activation effect of catalase.

Tang C, Gao R, Tang X, Zhang Y, Feng W, Feng B Chin Herb Med. 2024; 16(2):227-230.

PMID: 38706817 PMC: 11064617. DOI: 10.1016/j.chmed.2022.12.009.

Structure Revision of Penipacids A-E Reveals a Putative New Cryptic Natural Product, -aminoanthranilic Acid, with Potential as a Transcriptional Regulator of Silent Secondary Metabolism.

Khalil Z, Kankanamge S, Capon R Mar Drugs. 2022; 20(6).

PMID: 35736142 PMC: 9225364. DOI: 10.3390/md20060339.

Antibacterial Polyketides from Antarctica Sponge-Derived Fungus sp. HDN151272.

Shah M, Sun C, Sun Z, Zhang G, Che Q, Gu Q Mar Drugs. 2020; 18(2).

PMID: 31979231 PMC: 7073682. DOI: 10.3390/md18020071.

Novel Natural Products from Extremophilic Fungi.

Zhang X, Li S, Li J, Liang Z, Zhao C Mar Drugs. 2018; 16(6).

PMID: 29867059 PMC: 6025453. DOI: 10.3390/md16060194.