Characterization of Staphylococcus Aureus from Human Immunodeficiency Virus (HIV) Patients in Accra, Ghana

Overview

Journal J Infect Dev Ctries

Specialty Infectious Diseases

Date 2016 Jun 2

PMID 27249519

Citations 11

Authors

Beverly Egyir

Akwasi Ampofo Oteng

Enid Owusu

Mercy Jemimah Newman

Kennedy Kwasi Addo

Anders Rhod-Larsen

Affiliations

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Abstract

Introduction: The aims of this study were to: a) determine the nasal carriage prevalence of Stahpylococcus aureus among HIV patients, b) to characterize S. aureus strains isolated.

Methodology: Characterization of S. aureus isolates was done by antibiotyping, spa typing, and detection of Panton-Valentine leukocidin (PVL) genes.

Results: S. aureus isolated (10/124; 8%) belonged to spa types t084 (n = 3), t10828 (n = 2), t311, t304, t774, t645, and t091. The isolates were resistant to penicillin (100%), tetracycline (40%), rifampicin (10%), fucidic acid (10%), norfloxacin (10%), erythromycin (10%), and sulfamethoxazole trimethoprim (10%). Multidrug resistance (MDR) was detected in 30% of the isolates.

Conclusion: The finding of MDR S. aureus among HIV-positive patients suggests that surveillance of antimicrobial resistant S. aureus among this patient group could be considered as an infection control measure in the hospital.

Citing Articles

Nasopharyngeal Carriage and Antimicrobial Resistance among Adults with Sickle Cell Disease at the Korle Bu Teaching Hospital in Accra, Ghana.

Dayie N, Sekoh D, Tetteh-Quarcoo P, Dayie A, Osei M, Kotey F Microbiol Insights. 2022; 15:11786361221133959.

PMID: 36339725 PMC: 9629541. DOI: 10.1177/11786361221133959.

Prevalence and genetic lineages of nasal colonization and urinary tract infection among people living with HIV/AIDS in Nigeria: A systematic review.

Abdullahi I, Issaoui R, Usman Y IJID Reg. 2022; 4:17-24.

PMID: 36093365 PMC: 9453218. DOI: 10.1016/j.ijregi.2022.05.009.

Antimicrobial resistance and genomic analysis of staphylococci isolated from livestock and farm attendants in Northern Ghana.

Egyir B, Dsani E, Owusu-Nyantakyi C, Rabbi Amuasi G, Owusu F, Allegye-Cudjoe E BMC Microbiol. 2022; 22(1):180.

PMID: 35864456 PMC: 9306040. DOI: 10.1186/s12866-022-02589-9.

Methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage among patients with diabetes at the Korle Bu Teaching Hospital.

Anafo R, Atiase Y, Kotey F, Dayie N, Tetteh-Quarcoo P, Duodu S PLoS One. 2021; 16(9):e0257004.

PMID: 34534230 PMC: 8448364. DOI: 10.1371/journal.pone.0257004.

Methicillin-Resistant (MRSA) Infection of Diabetic Foot Ulcers at a Tertiary Care Hospital in Accra, Ghana.

Anafo R, Atiase Y, Dayie N, Kotey F, Tetteh-Quarcoo P, Duodu S Pathogens. 2021; 10(8).

PMID: 34451401 PMC: 8398970. DOI: 10.3390/pathogens10080937.