Factors Related to Curved Femur in Elderly Japanese Women

Overview

Journal Ups J Med Sci

Specialty General Medicine

Date 2016 May 27

PMID 27228191

Citations 5

Authors

Hiroyuki Tsuchie

Naohisa Miyakoshi

Yuji Kasukawa

Seietsu Senma

Yuichiro Narita

Seiya Miyamoto

Yuji Hatakeyama

Kana Sasaki

Yoichi Shimada

Affiliations

Soon will be listed here.

Abstract

Background: Multiple factors are involved in the development of atypical femoral fractures, and excessive curvature of the femur is thought to be one of them. However, the pathogenesis of femoral curvature is unknown. We evaluated the influence of factors related to bone metabolism and posture on the development of femoral curvature.

Methods: A total of 139 women participated in the present study. Curvatures were measured using antero-posterior and lateral radiography of the femur. We evaluated some bone and vitamin D metabolism markers in serum, the bone mineral density (BMD), lumbar spine alignment, and pelvic tilt.

Results: We divided the women into two groups, curved and non-curved groups, based on the average plus standard deviation as the cut-off between the groups. When univariate logistic regression analysis was performed to detect factors affecting femoral curvature, the following were identified as indices significantly affecting the curvature: age of the patients, serum concentrations of calcium, intact parathyroid hormone, pentosidine, homocysteine and 25-hydroxyvitamin D (25(OH)D), and BMD of the proximal femur (P < 0.05) both in the lateral and anterior curvatures. When we used multivariate analyses to assess these factors, only 25(OH)D and age (lateral and anterior standardized odds ratio: 0.776 and 0.385, and 2.312 and 4.472, respectively) affected the femoral curvature (P < 0.05).

Conclusion: Femoral curvature is strongly influenced by age and serum vitamin D.

Citing Articles

Factors Affecting the Second Complete Atypical Femoral Fracture after the First Atypical Fracture.

Tsuchie H, Kasukawa Y, Nozaka K, Kinoshita H, Sasaki K, Aizawa T Med Princ Pract. 2023; 33(1):10-20.

PMID: 38104544 PMC: 10896619. DOI: 10.1159/000535759.

Femoral Bowing Increases Early Postoperative Stress around the Femoral Stem in Humans: A Finite Element Analysis.

Kaku N, Hosoyama T, Shibuta Y, Tsumura H Clin Orthop Surg. 2023; 15(5):725-733.

PMID: 37811508 PMC: 10551689. DOI: 10.4055/cios22392.

Influence of femoral bowing on stress distribution of the proximal femur: a three-dimensional finite element analysis.

Kaku N, Hosoyama T, Shibuta Y, Kimura M, Tsumura H J Orthop Surg Res. 2023; 18(1):82.

PMID: 36721221 PMC: 9890711. DOI: 10.1186/s13018-023-03559-1.

Evaluation of the Nature and Etiologies of Risk Factors for Diaphyseal Atypical Femoral Fractures.

Tsuchie H, Miyakoshi N, Kasukawa Y, Nozaka K, Saito K, Kinoshita H Med Princ Pract. 2021; 30(5):430-436.

PMID: 34058735 PMC: 8562049. DOI: 10.1159/000517484.

Population-based, three-dimensional analysis of age- and sex-related femur shaft geometry differences.

Jung I, Choi E, Lee B, Kim J Osteoporos Int. 2021; 32(8):1631-1638.

PMID: 33501569 DOI: 10.1007/s00198-021-05841-6.

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