Local Staging and Assessment of Colon Cancer with 1.5-T Magnetic Resonance Imaging

Overview

Journal Br J Radiol

Publisher Oxford University Press

Specialty Radiology

Date 2016 May 27

PMID 27226219

Citations 13

Authors

Chris Hunter

Helena Blake

Nelesh Jeyadevan

Muti Abulafi

Ian Swift

Paul Toomey

Gina Brown

Affiliations

Soon will be listed here.

Abstract

Objective:: The aim of this study was to assess the accuracy of 1.5-T MRI in the pre-operative local T and N staging of colon cancer and identification of extramural vascular invasion (EMVI).

Methods:: Between 2010 and 2012, 60 patients with adenocarcinoma of the colon were prospectively recruited at 2 centres. 55 patients were included for final analysis. Patients received pre-operative 1.5-T MRI with high-resolution T weighted, gadolinium-enhanced T weighted and diffusion-weighted images. These were blindly assessed by two expert radiologists. Accuracy of the T-stage, N-stage and EMVI assessment was evaluated using post-operative histology as the gold standard.

Results:: Results are reported for two readers. Identification of T3 disease demonstrated an accuracy of 71% and 51%, sensitivity of 74% and 42% and specificity of 74% and 83%. Identification of N1 disease demonstrated an accuracy of 57% for both readers, sensitivity of 26% and 35% and specificity of 81% and 74%. Identification of EMVI demonstrated an accuracy of 74% and 69%, sensitivity 63% and 26% and specificity 80% and 91%.

Conclusion:: 1.5-T MRI achieved a moderate accuracy in the local evaluation of colon cancer, but cannot be recommended to replace CT on the basis of this study.

Advances In Knowledge:: This study confirms that MRI is a viable alternative to CT for the local assessment of colon cancer, but this study does not reproduce the very high accuracy reported in the only other study to assess the accuracy of MRI in colon cancer staging.

Citing Articles

Comparative evaluation of CT and MRI in the preoperative staging of colon cancer.

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Evaluation of colon cancer prognostic factors by CT and MRI: an up-to-date review.

Guimaraes R, Pacheco E, Ueda S, Tiferes D, Mazzucato F, Talans A Abdom Radiol (NY). 2024; 49(11):4003-4015.

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MRI Evaluation of Rectal Cancer Lymph Node Staging Using Apparent Diffusion Coefficient.

Pikuniene I, Saladzinskas Z, Basevicius A, Straksyte V, Zilinskas J, Ambraziene R Cureus. 2023; 15(9):e45002.

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CT and 3 Tesla MRI in the TN Staging of Colon Cancer: A Prospective, Blind Study.

Rafaelsen S, Dam C, Vagn-Hansen C, Moller J, Rahr H, Sjostrom M Curr Oncol. 2022; 29(2):1069-1079.

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