Cerebral Salt Wasting Syndrome Following Head Injury in a Child Managed Successfully with Fludrocortisone

Overview

Journal Case Rep Pediatr

Publisher Wiley

Specialty Pediatrics

Date 2016 May 24

PMID 27213068

Citations 4

Authors

Nagendra Chaudhary

Santosh Pathak

Murli Manohar Gupta

Nikhil Agrawal

Affiliations

Soon will be listed here.

Abstract

Cerebral salt wasting (CSW) syndrome is an important cause of hyponatremia in head injuries apart from syndrome of inappropriate antidiuretic hormone (SIADH). Proper diagnosis and differentiation between these two entities are necessary for management as the treatment is quite opposite in both conditions. Fludrocortisone can help in managing CSW where alone saline infusion does not work. We report a 17-month-old female child with head injury managed successfully with saline infusion and fludrocortisone.

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References

Dubuis J, Girardin E, Rimensberger P . Acute symptomatic hyponatremia and cerebral salt wasting after head injury: an important clinical entity. J Pediatr Surg. 2001; 36(7):1094-7. DOI: 10.1053/jpsu.2001.24770. View

Ganong C, KAPPY M . Cerebral salt wasting in children. The need for recognition and treatment. Am J Dis Child. 1993; 147(2):167-9. DOI: 10.1001/archpedi.1993.02160260057022. View

KAPPY M, Ganong C . Cerebral salt wasting in children: the role of atrial natriuretic hormone. Adv Pediatr. 1996; 43:271-308. View

Yee A, Burns J, Wijdicks E . Cerebral salt wasting: pathophysiology, diagnosis, and treatment. Neurosurg Clin N Am. 2010; 21(2):339-52. DOI: 10.1016/j.nec.2009.10.011. View

Kinik S, Kandemir N, Baykan A, Akalan N, Yordam N . Fludrocortisone treatment in a child with severe cerebral salt wasting. Pediatr Neurosurg. 2001; 35(4):216-9. DOI: 10.1159/000050424. View

Berendes E, Walter M, Cullen P, Prien T, Van Aken H, Horsthemke J . Secretion of brain natriuretic peptide in patients with aneurysmal subarachnoid haemorrhage. Lancet. 1997; 349(9047):245-9. DOI: 10.1016/s0140-6736(96)08093-2. View

Sakarcan A, Bocchini Jr J . The role of fludrocortisone in a child with cerebral salt wasting. Pediatr Nephrol. 1999; 12(9):769-71. DOI: 10.1007/s004670050543. View

Cerda-Esteve M, Cuadrado-Godia E, Chillaron J, Pont-Sunyer C, Cucurella G, Fernandez M . Cerebral salt wasting syndrome: review. Eur J Intern Med. 2008; 19(4):249-54. DOI: 10.1016/j.ejim.2007.06.019. View

von Bismarck P, Ankermann T, Eggert P, Claviez A, Fritsch M, Krause M . Diagnosis and management of cerebral salt wasting (CSW) in children: the role of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Childs Nerv Syst. 2006; 22(10):1275-81. DOI: 10.1007/s00381-006-0091-x. View

10.

Nagotkar L, Shanbag P, Dasarwar N . Cerebral salt wasting syndrome following neurosurgical intervention in tuberculous meningitis. Indian Pediatr. 2008; 45(7):598-601. View

11.

Nelson P, Seif S, Maroon J, Robinson A . Hyponatremia in intracranial disease: perhaps not the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). J Neurosurg. 1981; 55(6):938-41. DOI: 10.3171/jns.1981.55.6.0938. View

12.

Leonard J, Garrett R, Salottolo K, Slone D, Mains C, Carrick M . Cerebral salt wasting after traumatic brain injury: a review of the literature. Scand J Trauma Resusc Emerg Med. 2015; 23:98. PMC: 4642664. DOI: 10.1186/s13049-015-0180-5. View

13.

Jabbar A, Farrukh S, Khan R . Cerebral salt wasting syndrome in tuberculous meningitis. J Pak Med Assoc. 2011; 60(11):964-5. View

14.

Chung H, Kluge R, Schrier R, Anderson R . Clinical assessment of extracellular fluid volume in hyponatremia. Am J Med. 1987; 83(5):905-8. DOI: 10.1016/0002-9343(87)90649-8. View

15.

Peters J, Welt L, SIMS E, ORLOFF J, Needham J . A salt-wasting syndrome associated with cerebral disease. Trans Assoc Am Physicians. 1950; 63:57-64. View

16.

Harrigan M . Cerebral salt wasting syndrome: a review. Neurosurgery. 1996; 38(1):152-60. DOI: 10.1097/00006123-199601000-00035. View

17.

Ishikawa S, Saito T, Kaneko K, Okada K, Kuzuya T . Hyponatremia responsive to fludrocortisone acetate in elderly patients after head injury. Ann Intern Med. 1987; 106(2):187-91. DOI: 10.7326/0003-4819-106-2-187. View

18.

Ozdemir H, Aycan Z, Degerliyurt A, Metin A . The treatment of cerebral salt wasting with fludrocortisone in a child with lissencephaly. Turk Neurosurg. 2010; 20(1):100-2. View

19.

Berkenbosch J, Lentz C, Jimenez D, Tobias J . Cerebral salt wasting syndrome following brain injury in three pediatric patients: suggestions for rapid diagnosis and therapy. Pediatr Neurosurg. 2002; 36(2):75-9. DOI: 10.1159/000048356. View

20.

Taplin C, Cowell C, Silink M, Ambler G . Fludrocortisone therapy in cerebral salt wasting. Pediatrics. 2006; 118(6):e1904-8. DOI: 10.1542/peds.2006-0702. View