Review of the Pharmacological Effects of Vitis Vinifera (Grape) and Its Bioactive Constituents: An Update

Overview

Journal Phytother Res

Publisher Wiley

Date 2016 May 20

PMID 27196869

Citations 76

Authors

Marjan Nassiri-Asl

Hossein Hosseinzadeh

Affiliations

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Abstract

Vitis vinifera fruit (grape) contains various phenolic compounds, flavonoids and stilbenes. In recent years, active constituents found in the fruits, seeds, stems, skin and pomaces of grapes have been identified and some have been studied. In this review, we summarize the active constituents of different parts of V. vinifera and their pharmacological effects including skin protection, antioxidant, antibacterial, anticancer, antiinflammatory and antidiabetic activities, as well as hepatoprotective, cardioprotective and neuroprotective effects in experimental studies published after our 2009 review. Clinical and toxicity studies have also been examined. Copyright © 2016 John Wiley & Sons, Ltd.

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