Keratocystic Odontogenic Tumors Related to Gorlin-Goltz Syndrome: A Clinicopathological Study

Overview

Journal J Oral Biol Craniofac Res

Publisher Elsevier

Date 2016 May 20

PMID 27195205

Citations 3

Authors

Mohammed Israr Ul Khaliq

Ajaz A Shah

Irshad Ahmad

Shahid Hasan

Sagar S Jangam

Farah

Anwar

Affiliations

Soon will be listed here.

Abstract

Background: Assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with Gorlin-Goltz syndrome in our institution from 2004 to 2015.

Method: After histopathological analyses of KCOT related to Gorlin-Goltz syndrome, 7 patients were assessed. These patients presented a total of 15 primary and 2 recurrent KCOT.

Results: All patients presented a multiple KCOT, and 13 lesions were located in mandible (77%) and 4 (23%) in maxilla. Most of the tumors presented a unilocular pattern (71%) and had tooth association (88%). Four patients (57%) were in the age group of 10-19 years and three patients (43%) were in the age group of 20-29 years. There were four male and three female patients.

Conclusion: KCOT is a frequent manifestation of Gorlin-Goltz syndrome and can be its first sign, mainly in young patients. The four patients presented with two lesions (57%) and three lesions in three patients (43%).

Citing Articles

Radiological evaluation of odontogenic keratocysts in patients with nevoid basal cell carcinoma syndrome: A review.

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Gorlin Syndrome: Recent Advances in Genetic Testing and Molecular and Cellular Biological Research.

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Multidisciplinary oral rehabilitation of an adolescent suffering from juvenile Gorlin-Goltz syndrome - a case report.

Nilius M, Kohlhase J, Lorenzen J, Lauer G, Schulz M Head Face Med. 2019; 15(1):5.

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